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Lian Qiang,Tang Simiao,Zhu Longxiang,Zhang Luteng,Sun Wan,Bu Shanshan,Pan Liangming,Tian Wenxi,Qiu Suizheng,Su G.H.,Wu Xinghua,Wang Xiaoyu 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.11
Blanket is of vital importance for engineering application of the fusion reactor. Nuclear heat deposition in materials is the main heat source in blanket structure. In this paper, the three-dimensional method for thermalhydraulics/ neutronics coupling analysis is developed and applied for the full-scale module of the helium-cooled ceramic breeder tritium breeding blanket (HCCB TBB) designed for China Fusion Engineering Test Reactor (CFETR). The explicit coupling scheme is used to support data transfer for coupling analysis based on cell-to-cell mapping method. The coupling algorithm is realized by the user-defined function compiled in Fluent. The threedimensional model is established, and then the coupling analysis is performed using the paralleled Coupling Analysis of Thermal-hydraulics and Neutronics Interface Code (CATNIC). The results reveal the relatively small influence of the coupling analysis compared to the traditional method using the radial fitting function of internal heat source. However, the coupling analysis method is quite important considering the nonuniform distribution of the neutron wall loading (NWL) along the poloidal direction. Finally, the structure optimization of the blanket is carried out using the coupling method to satisfy the thermal requirement of all materials. The nonlinear effect between thermal-hydraulics and neutronics is found during the blanket structure optimization, and the tritium production performance is slightly reduced after optimization. Such an adverse effect should be thoroughly evaluated in the future work.
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Meng Liu,Yilun Deng,Yajun Cheng,Zilong Hao,Simiao Wu,Ming Liu 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.7
Purpose: Plasma osmolality, a marker of dehydration, is associated with cardiovascular mortality. We aimed to investigatewhether elevated plasma osmolality is associated with case fatality within 1 year after severe acute ischemic stroke. Materials and Methods: We included severe ischemic stroke patients (defined as National Institutes of Health Stroke Scale ≥15score) within 24 hours from symptom onset admitted to the Department of Neurology, West China Hospital between January 2017and June 2019. Admission plasma osmolality was calculated using the equation 1.86*(sodium+potassium)+1.15*glucose+urea+14. Elevated plasma osmolality was defined as plasma osmolality >296 mOsm/kg, indicating a state of dehydration. Study outcomesincluded 3-month and 1-year case fatalities. Multivariable logistic regression was performed to determine independent associationsbetween plasma osmolality and case fatalities at different time points. Results: A total of 265 patients with severe acute ischemic stroke were included. The mean age was 71.2±13.1 years, with 51.3%being males. Among the included patients, case fatalities were recorded for 31.7% (84/265) at 3 months and 39.6% (105/265) at1 year. Elevated plasma osmolality (dehydration) was associated with 3-month case fatality [odds ratio (OR) 1.98, 95% confidenceinterval (CI) 1.07–3.66, p=0.029], but not 1-year case fatality (OR 1.51, 95% CI 0.84–2.72, p=0.165), after full adjustment for confoundingfactors. Conclusion: Elevated plasma osmolality was independently associated with 3-month case fatality, but not 1-year case fatality, forsevere acute ischemic stroke.
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