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      • Knowledge and Perceptions about Colorectal Cancer in Jordan

        Taha, Hana,Jaghbeer, Madi Al,Shteiwi, Musa,AlKhaldi, Sireen,Berggren, Vanja Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.18

        Background: Colorectal cancer (CRC) is the third most common cancer globally. In Jordan, it is the number one cancer among men and the second most common cancer among women, accounting for 15% and 9.4% respectively of all male and female diagnosed cancers. This study aimed to evaluate the knowledge and perceptions about colorectal cancer risk factors, signs and symptoms in Jordan and to provide useful data about the best modes of disseminating preventive messages about the disease. Materials and Methods: A stratified clustered random sampling technique was used to recruit 300 males and 300 females aged 30 to 65 years without a previous history of CRC from four governorates in Jordan. A semi-structured questionnaire and face to face interviews were employed. Descriptive and multivariate analysis was applied to assess knowledge and perceptions about CRC. Results: Both males and females perceived their CRC risk to be low. They had low knowledge scores about CRC with no significant gender association (P=0.47). From a maximum knowledge score of 18 points, the median scores of males and females were 4 points (SD=2.346, range 0-13) and 4 points (SD=2.329, range 0-11) respectively. Better knowledge scores were associated with governorate, higher educational level, older age, higher income, having a chronic disease, having a family history of CRC, previously knowing someone who had CRC and their doctor's knowledge about their family history of CRC. Conclusions: There is a low level of knowledge about CRC and underestimation of risk among the study participants. This underlines the need for public health interventions to create awareness about the illness. It also calls for further research to assess the knowledge and perceptions about CRC early detection examinations in Jordan.

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        Natural dye-sensitized ZnO nano-particles as photo-catalysts in complete degradation of E. coli bacteria and their organic content

        Zyoud, A.,Dwikat, M.,Al-Shakhshir, S.,Ateeq, S.,Shteiwi, J.,Zu'bi, A.,Helal, M.H.S.,Campet, G.,Park, D.,Kwon, H.,Kim, T.W.,Kharoof, M.,Shawahna, R.,Hilal, H.S. Elsevier Sequoia 2016 Journal of photochemistry and photobiology Chemist Vol.328 No.-

        <P>This communication describes for the first time how nano-size particles, sensitized with natural dye molecules of anthocyanin, can be used as catalysts in photo-degradation of gram negative Escherichia coli bacteria in water. The naked ZnO nano-particles degraded up to 83% of the bacteria under solar simulator light, while the dye-sensitized particles increased the bacterial loss by similar to 10%. Solar simulator light includes about 5% of UV tail (shorter than 400 nm) which means that both UV and visible light (longer than 400 nm) radiations could be involved. When a cut-off filter was used, the naked ZnO caused only 40% bacterial loss, in accordance with earlier literature that described killing of bacteria with ZnO particles both in the dark and under light. With the cut-off filter, the sensitized ZnO particles caused higher than 90% bacterial loss, which confirms sensitization of the ZnO particles to visible light. Moreover, the results show that the catalyzed photo-degradation process causes mineralization of the bacteria and their organic internal components which leach out by killing. The catalyst can be recovered and reused losing similar to 10% of its activity each time due to mineralization of the dye molecules. However, catalyst activity can be totally regained by re-sensitizing it with the anthocyanin dye. The effects of different experimental conditions, such as reaction temperature, pH, bacterial concentration and catalyst amount together with nutrient broth and saline media, will be discussed together with the role of the sensitizer. (C) 2016 Elsevier B.V. All rights reserved.</P>

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        Lattice radiotherapy in inflammatory breast cancer: report of a first case treated with curative aim

        Parisi Silvana,Sciacca Miriam,Critelli Paola,Ferrantelli Giacomo,Chillari Federico,Venuti Valeria,Napoli Claudio,Shteiwi Issa,Siragusa Carmelo,Brogna Anna,Pontoriero Antonio,Ferini Gianluca,Santacater 대한방사선종양학회 2024 대한방사선종양학회지 Vol.42 No.2

        Inflammatory breast cancer (IBC) is a rare, aggressive form of breast cancer characterized by poor prognosis. The treatment requires a multidisciplinary approach, with neoadjuvant chemotherapy, surgery, and radiation therapy (RT). Particularly, high doses of conventional RT have been historically delivered in the adjuvant setting after chemotherapy and mastectomy or as radical treatment in patients ineligible for surgery. Here, we report the case of a 49-year-old woman patient with IBC unsuitable for surgery and treated with a combination of lattice RT and fractionated external beam RT concurrent with trastuzumab, with a curative aim. One year after RT, the patient showed a complete response and tolerable toxicities. This is the first reported case of a not-operable IBC patient treated with this particular kind of RT.

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