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      • Inhibition of Mast Cells by Algae

        Joseph A. Price III,Charles Sanny,Dennis Shevlin 한국식품영양과학회 2002 Journal of medicinal food Vol.5 No.4

        There is a history of use of algae as foods and as food aditives, or nutraceuticals. Althoughalgae are a safe component of human foods and animal feds, the effects of the algae otherthan as a source of protein are not clear. We examined the prevalence of an antiinflammatoryactivity in selected algae using, as an assay system, the inhibition of histamine release frommast cells. Methanolic extracts of eleven algae were examined for activity to inhibit the re-lease of histamine from mast cells in vitro. This activity was found widely among the sam-ples tested. The activities of these extracts were not uniformly stable in acid methanol. Se-lected extracts studied further did not separate with the use of size-exclusion filtration filters.LH-20 chromatography suggested at least two main elution areas of activity of the Chlorellaextract. In sumary, we saw wide phylogenetic dispersion of mast cell inhibition activity,suggesting that this antiinflammatory property is common in algae. This effect was apar-ently due to multiple activities within the algal extracts.205

      • Polymorph Engineering of TiO<sub>2</sub>: Demonstrating How Absolute Reference Potentials Are Determined by Local Coordination

        Buckeridge, John,Butler, Keith T.,Catlow, C. Richard A.,Logsdail, Andrew J.,Scanlon, David O.,Shevlin, Stephen A.,Woodley, Scott M.,Sokol, Alexey A.,Walsh, Aron American Chemical Society 2015 Chemistry of materials Vol.27 No.11

        <P>We report that the valence and conduction band energies of TiO<SUB>2</SUB> can be tuned over a 4 eV range by varying the local coordination environments of Ti and O. We examine the electronic structure of eight known polymorphs and align their ionization potential and electron affinity relative to an absolute energy reference, using an accurate multiscale quantum-chemical approach. For applications in photocatalysis, we identify the optimal combination of phases to enhance activity in the visible spectrum. The results provide a coherent explanation for a wide range of phenomena, including the performance of TiO<SUB>2</SUB> as an anode material for Li-ion batteries, allow us to pinpoint hollandite TiO<SUB>2</SUB> as a new candidate transparent conducting oxide, and serve as a guide to improving the efficiency of photo-electrochemical water splitting through polymorph engineering of TiO<SUB>2</SUB>.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/cmatex/2015/cmatex.2015.27.issue-11/acs.chemmater.5b00230/production/images/medium/cm-2015-00230v_0006.gif'></P>

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