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RISS 인기검색어
- 검색키워드
- 저자 : Shang-Wen Yao (검색결과 3 건)
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Involvement of MicroRNA-198 Overexpression in the Poor Prognosis of Esophageal Cancer
Qi, Bo,Yao, Wen-Jian,Zhao, Bao-Sheng,Qin, Xiu-Guang,Wang, Yi,Wang, Wen-Ju,Wang, Tian-Yun,Liu, Shang-Guo,Li, Han-Chen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9
Objective: This study aimed to investigate whether the miR-198 expression level is related to clinicopathological factors and prognosis of esophageal cancer. Methods: MicroRNA was extracted from esophageal cancer patients who underwent surgery for assessment using the Taqman@ MicroRNA assay. The correlation between miR-198 expression and clinicopathological features was analyzed, and the significance of miR-198 as a prognostic factor and its relationship with survival was determined. Results: MicroRNA-198 (miR-198) expression was higher in patients with poor prognosis than those with good prognosis (P<0.05). Kaplan-Meier analysis results showed that the miR-198 expression level had a significant correlation with survival time (P=0.030) and that patients with a higher expression of miR-198 had a shorter survival time. Cox multi-factor model analysis showed that patient prognosis (P=0.014), tumor length (P=0.040) and expression (P=0.012), and survival time had a significant correlation; the corresponding risks were 7.268, 1.246, and 3.524, respectively. Conclusion: miR-198 overexpression is involved in the poor prognosis of esophageal cancer and can be used as a biomarker for selection of cases requiring especial attention.
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Dung, Dinh Van,Shang, Weiwei,Yao, Wen Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.6
The effect of concentrate mixtures with crude protein (CP) levels 10%, 13%, 16%, and 19% and diets with roughage to concentrate ratios 80:20, 60:40, 40:60, and 20:80 (w/w) were determined on dry matter (DM) and organic matter (OM) digestibility, and fermentation metabolites using an in vitro fermentation technique. In vitro fermented attributes were measured after 4, 24, and 48 h of incubation respectively. The digestibility of DM and OM, and total volatile fatty acid (VFA) increased whereas pH decreased with the increased amount of concentrate in the diet (p<0.001), however CP levels of concentrate did not have any influence on these attributes. Gas production reduced with increased CP levels, while it increased with increasing concentrate levels. Ammonia nitrogen ($NH_3$-N) concentration and microbial CP production increased significantly (p<0.05) by increasing CP levels and with increasing concentrate levels in diet as well, however, no significant difference was found between 16% and 19% CP levels. Therefore, 16% CP in concentrate and increasing proportion of concentrate up to 80% in diet all had improved digestibility of DM and organic matter, and higher microbial protein production, with improved fermentation characteristics.
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Photocatalytic degradation of toluene in a staged fluidized bed reactor using TiO2/silica gel
Hsiu-Po Kuo,Shang-Wen Yao,An-Ni Huang,Wan-Yi Hsu 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.1
Relatively high concentration toluene is photocatalytically degraded in a multi-stage fluidized bed reactor continuously. The fluidizing media are titanium dioxide deposited silica gel particles, which are prepared by the doping sol-gel method. The effects of the Ti/Si atomic ratio, the inlet gas flow rates, and the number of the stages on the toluene removal efficiency were evaluated. The highest toluene removal efficiency is obtained when the fluidizing media are with the Ti/Si atomic ratio of 1.25. The apparent reaction orders are 0.4-0.5 for the single-stage system and 0.7 for the two-stage system, respectively. With an inlet toluene concentration of 1,000 ppm, a relative humidity of 30% and a volumetric flow rate of 10 L/min, the removal efficiency of toluene at the steady state is as high as 80% and is maintained in the 6-hr experimental time.
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