http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Shaimaa A Habib (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Promising Fe3O4/CdSe Nanocomposites for Rug Delivery in Liver Cancer Treatment
( Shaimaa A. Habib ),( M. B. Mohamed ),( S. A. Saafan ),( T. M. Meaz ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Nowadays, magnetic semiconductors nanocomposites have become a new class of materials of great importance promising with new properties and exploiting unique incorporation between materials. For example, one can make use of a variety of spin-related phenomena, not readily available in other materials. this work concentrates on synthesis of magnetic iron oxide nanoparticles (MNs) and Cadmium Selenide (CdSe) quantum dots (QDs). CdSe QDs have attractive optical properties such as bright fluorescence emission and wide absorption band in the visible region and they possess the ability to act as energy donors through Förster resonance energy transfer (FRET). MNs also are known to have interesting applications in biomedical field and drug delievery system. Methods: In the present work, bi-functional magnetic-luminescent nanocomposites with Fe<sub>3</sub>O<sub>4</sub> nanoparticles as the cores and CdSe as the shells have been synthesized by a facile direct precipitation method. Transmission electron microscopy (TEM) images revealed that the obtained bi-functional nanocomposites had a core-shell structure. The flower shape has been ascribed to the inhomogeneous growth of CdSe due to the presence of many active sites which turn to be nucleation centers for the CdSe on the surface of the nano-magnetite. The X-ray diffraction (XRD) patterns ensured the cubic spinel structure of the Fe<sub>3</sub>O<sub>4</sub> core. Results: Magnetic measurements indicated that the presence of CdSe in the composite has reduced its magnetic properties. Optical measurements of the Fe<sub>3</sub>O<sub>4</sub>/CdSe nanocomposites showed that the prepared samples have dual functions, optical tunable band gap similar to the semiconductor quantum dots and magnetic properties due to Fe<sub>3</sub>O<sub>4</sub> nanoparticles. According to the values of Stokes shift of the new hybrid composites, one can suggest that they may be promising in drug delivery (liver cancer treatment). All of the first line of result idicate that all of fabricated samples are so promising in drug delivery system. Conclusions: Fe<sub>3</sub>O<sub>4</sub> nanoparticles has been successfully prepared by the co-precipetation method. The have been investigated via XRD, TEM and VSM. The XRD confirms the formation of the required cubic ferrite without other unwanted phases. The Fe<sub>3</sub>O<sub>4</sub>has been used as a seed or as a core to grow CdSe nanoshell around. The obtained hybrid Fe<sub>3</sub>O<sub>4</sub> nanostructure has flower shape particles. The Fe<sub>3</sub>O<sub>4</sub>/CdSe nanocomposites has larger quantum yield values thanthose of pure CdSe QDs may be due to the fact that magnetic nanoparticles facilitate the electron holerecombination and enhance the emission from the quantum dots. In other words, the presence of Fe<sub>3</sub>O<sub>4</sub> enhances the optical properties of CdSe quantum dots. The prepared nanocomposites have dual functions, optical tunable band gap similar to the semiconductor quantum dots and magnetic properties due to Fe<sub>3</sub>O<sub>4</sub>nanoparticles. This composite would be considered as dilute magnetic-semiconductor and could be used in spintronics, biosensors, solarcells and biomedical lables which could confirm that these nanoparticles could be a suitable drug delievery tool for many anticancer agent in the future.
-
Rehab M. Hamdy,Shaimaa A Habib,Layla A Mohamed,Ola H. Abd Elaziz 한국심초음파학회 2022 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.30 No.4
BACKGROUND: In many cardiovascular disorders, the contractile performance of the right ventricle (RV) is the primary determinant of prognosis. For evaluating RV volumes and function, 4 dimensional (4D)-echocardiography has become common. This research used 2D and 4D modalities to assess RV contractile performance in hypertensive patients. METHODS: A total of 150 patients with essential hypertension were enrolled in this study, along with 75 age and sex-matched volunteers. Clinical evaluation and echocardiographic examination (including M-mode, tissue Doppler imaging, and 2D speckle tracking) were conducted on all participants. RV volumes, 4D-ejection fraction (EF), 4D-fractional area change (FAC), 4D-tricuspid annular plane systolic excursion (TAPSE), 4D-septal and free wall (FW) strain were all measured using 4D-echocardiography. RESULTS: Hypertensive patients showed 2D-RV systolic and diastolic dysfunction (including TAPSE, 2D-right ventricular global longitudinal strain, RV-myocardial performance index and average E/EaRV) and 4D-RV impairment (including right ventricular EF, FAC, RV strain and TAPSE, right ventricular end-diastolic volume and right ventricular end-systolic volume) compared to the control group. We verified the prevalence of RV systolic dysfunction in hypertension patients using the following parameters: 1) 15% of them had 2D-TAPSE < 17 mm vs. 40% by 4D-TAPSE; 2) 25% of them had 2D-GLS < 19% vs. 42% by 4D-septal strain and 35% by 4D FW strain; 3) 35% of hypertensive patients had 4D-EF < 45%; and finally; 4) 25% of hypertensive patients had 2D-FAC < 35% compared to 45% by 4D-FAC. CONCLUSIONS: The incidence of RV involvement was greater in 4D than in 2D-modality trans-thoracic echocardiography. We speculated that 4D-echocardiography with 4D-strain imaging would be more beneficial for examining RV morphology and function in hypertensive patients than 2D-echocardiography, since 4D-echocardiography could estimate RV volumes and function without making geometric assumptions.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
