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Asma Ashraf Khan,Adil Gani,Mudasir Ahmad,Farooq Ahmad Masoodi,Furheen Amin,Shaheen Kousar 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.4
This study evaluates the antioxidant, antimicrobial, and antiproliferative activities ofmushroom varieties (Agaricus bisporus, Pleurotus ostreatus, and Coprinus atramentarius) found in theHimalayan regions of Jammu and Kashmir, India. All three mushroom varieties exhibited antioxidantactivity. A. bisporus showed the highest diphenyl-2-picrylhydrazyl inhibition activity (87.88±5.6%), C. atramentarius showed the highest reducing power (0.49±0.01) and metal chelating ability (48.57±0.38%), and P. ostreatus contained the highest phenolic (5.25±0.14 mg gallic acid equivalent per gram)and flavonoid content (64.39±0.73 μg rutin equivalent per gram). C. atramentarius showed maximumantibacterial activity against all the pathogenic strains and the highest zone of inhibition was against S. typhi (7.45±0.5 mm). P. ostreatus exhibited the highest cell proliferation inhibition against Colo-205and MCF-7 cancer cell lines. The structural analysis by Fourier transform infrared spectroscopyindicated the presence of β-configuration in carbohydrates, phenolic compounds, and protein, whichimpart nutraceutical properties to mushrooms.
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Khan, Asma Ashraf,Gani, Adil,Ahmad, Mudasir,Masoodi, Farooq Ahmad,Amin, Furheen,Kousar, Shaheen 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.4
This study evaluates the antioxidant, antimicrobial, and antiproliferative activities of mushroom varieties (Agaricus bisporus, Pleurotus ostreatus, and Coprinus atramentarius) found in the Himalayan regions of Jammu and Kashmir, India. All three mushroom varieties exhibited antioxidant activity. A. bisporus showed the highest diphenyl-2-picrylhydrazyl inhibition activity ($87.88{\pm}5.6%$), C. atramentarius showed the highest reducing power ($0.49{\pm}0.01$) and metal chelating ability ($48.57{\pm}0.38%$), and P. ostreatus contained the highest phenolic ($5.25{\pm}0.14mg$ gallic acid equivalent per gram) and flavonoid content ($64.39{\pm}0.73{\mu}g$ rutin equivalent per gram). C. atramentarius showed maximum antibacterial activity against all the pathogenic strains and the highest zone of inhibition was against S. typhi ($7.45{\pm}0.5mm$). P. ostreatus exhibited the highest cell proliferation inhibition against Colo-205 and MCF-7 cancer cell lines. The structural analysis by Fourier transform infrared spectroscopy indicated the presence of ${\beta}-configuration$ in carbohydrates, phenolic compounds, and protein, which impart nutraceutical properties to mushrooms.
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Shah Syed Bilal,Sartaj Lubna,Hussain Shahid,Ullah Nabi,Idrees Muhammad,Shaheen Asma,Javed Muhammad Sufyan,Aslam Muhammad Kashif 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.2
Cannabis sativa (C. sativa) is a widespread medicinal plant used for humans and cattles infectious diseases. The current study is carried out to assess phytochemical, antimicrobial, antioxidant, α-amylase inhibition and cytotoxic activity of the Cannabis sativa plant. An appropriate amount of phytochemicals like tannins, flavonoids, lycopene, and β-carotenes is found in C. sativa plant during the phytochemical screening. Among these phytochemicals of C. sativa plant, tannin shows outstanding activity. The plant extracts are assessed for antimicrobial activity against different seven bacterial strains. Notably, the stem part of C. sativa is found to exhibit higher antimicrobial potential than root and leaf. Among the extracts, the antioxidant assays (evaluated through % inhibition of linoleic acid peroxidation assessment) of n-hexane extract of leaf part was highest (80.70%) compared to the others. The plant also contains a potent α-amylase inhibitory potential, the root extract shows maximum inhibition of α-amylase. The cytotoxic effect [evaluated through hemolytic activity as (%) lysis of RBCs against human erythrocytes] of the plant extracts is found insignificant ranging from 1.97 to 5.88. The plant C. sativa keeps a significant amount of bioactive phenolic combinations accompanied by high antimicrobial and antioxidant activities.
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