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RISS 인기검색어
- 검색키워드
- 저자 : Sarifuddin, Sarifuddin (검색결과 3 건)
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Physiological flow of shear-thinning viscoelastic fluid past an irregular arterial constriction
Sarifuddin,Santabrata Chakravarty,Prashanta Kumar Mandal 한국유변학회 2013 Korea-Australia rheology journal Vol.25 No.3
The present investigation deals with the effect of the shape of a stenosis on the flow characteristics of blood, having shear-thinning viscoelastic rheological properties by using a suitable mathematical model. Keeping the relevance of the physiological situation, the mathematical model is developed by treating blood as a non-Newtonian shear-thinning viscoelastic fluid characterised by unsteady Oldroyd-3-constant model through an axisymmetric irregular arterial stenosis obtained from casting of a mildly stenosed artery (cf. Back et al., 1984). Comparison with the well-known cosine-shaped stenosis, in order to estimate the effect of surface roughness on the flow characteristics of blood, has however not been ruled out from the present study. Numerical illustrations are presented for a physiological flow, as well as for an equivalent simple pulsatile flow with equal stroke volume to that of the physiological flow, and the differences in their flow behaviour are recorded and discussed. The Marker and Cell method is developed in cylindrical co-ordinate system in order to tackle the highly nonlinear governing equations of motion. The effects of the quantities of significance such as Reynolds number, Deborah number, blood viscoelasticity and flow pulsatility, as well on the velocity components, pressure drop, wall shear stress and patterns of streamlines are quantitatively investigated graphically. Comparison of the results reveals that although the behaviour of two different pulses are similar at the same instant of time, there exist some important deviations in the flow pattern, pressure drop and wall shear stress as well. The present results also predict that the excess pressure drop across the cosine stenosis compared with the irregular one is consistent with several existing results in the literature which substantiate sufficiently to validate the applicability of the model under consideration.
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Physiological flow of shear-thinning viscoelastic fluid past an irregular arterial constriction
Sarifuddin, Sarifuddin,Chakravarty, Santabrata,Mandal, Prashanta Kumar 한국유변학회 2013 Korea-Australia rheology journal Vol.25 No.3
The present investigation deals with the effect of the shape of a stenosis on the flow characteristics of blood, having shear-thinning viscoelastic rheological properties by using a suitable mathematical model. Keeping the relevance of the physiological situation, the mathematical model is developed by treating blood as a non-Newtonian shear-thinning viscoelastic fluid characterised by unsteady Oldroyd-3-constant model through an axisymmetric irregular arterial stenosis obtained from casting of a mildly stenosed artery (cf. Back et al., 1984). Comparison with the well-known cosine-shaped stenosis, in order to estimate the effect of surface roughness on the flow characteristics of blood, has however not been ruled out from the present study. Numerical illustrations are presented for a physiological flow, as well as for an equivalent simple pulsatile flow with equal stroke volume to that of the physiological flow, and the differences in their flow behaviour are recorded and discussed. The Marker and Cell method is developed in cylindrical co-ordinate system in order to tackle the highly nonlinear governing equations of motion. The effects of the quantities of significance such as Reynolds number, Deborah number, blood viscoelasticity and flow pulsatility, as well on the velocity components, pressure drop, wall shear stress and patterns of streamlines are quantitatively investigated graphically. Comparison of the results reveals that although the behaviour of two different pulses are similar at the same instant of time, there exist some important deviations in the flow pattern, pressure drop and wall shear stress as well. The present results also predict that the excess pressure drop across the cosine stenosis compared with the irregular one is consistent with several existing results in the literature which substantiate sufficiently to validate the applicability of the model under consideration.
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Wira Winardi,Widhy Yudistira Nalapraya,Sarifuddin Sarifuddin,Samsul Anwar,Amanda Yufika,Adityo Wibowo,Iziddin Fadhil,Hendra Wahyuni MS,Yunita Arliny,Dewi Behtri Yanifitri,Teuku Zulfikar,Harapan Harapa 대한예방의학회 2022 예방의학회지 Vol.55 No.5
Objectives: The Indonesian Ministry of Health launched isoniazid preventive therapy (IPT) in 2016, with general practitioners (GPs) at the frontline of this program. However, the extent to which GPs have internalized this program remains uncertain. The aim of this study was to identify the knowledge and attitudes of GPs towards the IPT program in Indonesia. Methods: This study used an online, self-administered questionnaire distributed via e-mail and social messaging services. A logistic regression model was employed to identify the explanatory variables influencing the level of knowledge and attitudes toward IPT among GPs in Indonesia. An empirical analysis was conducted separately for each response variable (knowledge and attitudes). Results: Of the 418 respondents, 128 (30.6%) had a good knowledge of IPT. Working at a public hospital was the only variable associated with good knowledge, with an adjusted odds ratio (aOR) of 1.69 (95% confidence interval [CI], 1.02 to 2.81). Furthermore, 279 respondents (66.7%) had favorable attitudes toward IPT. In the adjusted logistic regression analysis, good knowledge (aOR, 0.55; 95% CI, 0.34 to 0.89), 1-5 years of work experience (aOR, 2.09; 95% CI, 1.21 to 3.60), and having experienced IPT training (aOR, 0.48; 95% CI, 0.25 to 0.93), were significantly associated with favorable attitudes. Conclusions: In general, GPs in Indonesia had favorable attitudes toward IPT. However, their knowledge of IPT was limited. GPs are an essential element of the IPT program in the country, and therefore, adequate information dissemination to improve their understanding is critical for the long-term viability and quality of the IPT program in Indonesia.
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