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- 저자 : Saeed Masoum (검색결과 2 건)
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A microlagal-based carbonaceous sensor for enzymatic determination of glucose in blood serum
Seyed Mostafa Jafari,Saeed Masoum,Seyed Ali Hosseini Tafreshi 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.101 No.-
In the present work, Chlorella vulgaris, a well-known microalga was used as a carbonic precursor, tosynthesis the water-soluble carbon dots (CDs) via hydrothermal method. To improve the properties,acidic carbon dots (ACDs) were also synthesized via ultrasoncation of microalgal biomass after acidichydrolysis (using diluted acidic solution). The aqueous solution of ACDs was used as a sensor for glucosedetermination based on glucose oxidase enzyme (GOx) reaction and fluorescence quenching of ACDs inthe presence of Fe3+ ions under the optimized conditions. The linear range of glucose in the blood serumwas measured from a range of 5 mM to 500 mM with a limit of detection (LOD) 2.84 mM. Additionally, thehydrogen peroxide, as the conventional reactive oxygen species (ROS) was determined based on theFenton reaction. The linear range of H2O2 was obtained from 10 mM to 200 mM with LOD of 975 nM. Inall of these applications, fluorescence quenching of ACDs was followed according to photo-inducedelectron transfer (PET) mechanism in the presence of generated Fe3+ ions by Fenton reaction.
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Evaluation of Factors Impacting Cosmetic Outcome of Breast Conservative Surgery - a Study in Iran
Olfatbakhsh, Asiie,Mehrdad, Neda,Ebrahimi, Mandana,Alavi, Nasrin,Hashemi, Esmat,Kaviani, Ahmad,Najafi, Masoume,Haghighat, Shahpar,Arefanian, Saeed Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6
Background: Breast conservative surgery (BCS) followed by radiotherapy is the standard approach in management of stage I-II breast cancer. Several factors can affect cosmetic outcomes. The aim of this study was to evaluate the cosmetic results of BCS and influencing factors in the Iranian Breast Cancer Research Center. Materials and Methods: Patients who had undergone BCS were included. Photographs were taken of both breasts of the patients in three aspects and were evaluated by three specialists. The cosmetic scores were calculated based on a standard questionnaire. The data were analyzed using univariate and multivariate regression for relationships between cosmetic scores and clinical data. Results: A total number of 103 patients were included in the study. Mean age and BMI of the patients were $46.8{\pm}8.9$ and $28.1{\pm}3.9$, respectively. Breast cup sizes C and D accounted for 74.7% of the study group. The mean cosmetic score obtained from three referees was 5.72+2.06, consisting of 35.9% excellent-good, 35% moderate, and 29.1% unsatisfactory results. Patient BMI, volume of the resected tissue and breast cup size (D) showed significant correlation with the cosmetic score. On multivariate regression analysis, cosmetic score and BMI (p=0.022,) as well as breast cup size (p=0.040), remained significant. Conclusions: Immediate or delayed symmetrization of the breasts is suggested during breast conservative surgery, meanwhile performing oncoplastic techniques to improve the results significantly. Also it is suggested to discuss anticipation of less satisfactory results with patients having higher BMI and large breast cup size.
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