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RISS 인기검색어
- 검색키워드
- 저자 : Sadana, Devendra K. (검색결과 5 건)
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Heritability Estimates under Single and Multi-Trait Animal Models in Murrah Buffaloes
Jain, A.,Sadana, D.K. Asian Australasian Association of Animal Productio 2000 Animal Bioscience Vol.13 No.5
First lactation records of 683 Murrah buffaloes maintained at NDRI, Karnal which were progeny of 84 sires used for comparing the heritability estimates of age at first calving, first lactation milk yield and first service period under single and multiple trait models using restricted maximum likelihood (REML) method of estimation under an individual animal model. The results indicated that the heritability estimates may vary under single and multiple trait models depending upon the magnitude of genetic and environmental correlation among the traits being considered. Therefore, a single or multiple trait model is recommended for estimation of variance components depending upon the goal of breeding programme. However, there may not be any advantage of considering a trait with zero or near zero heritability and having no or very low genetic correlation with other traits in the model. Lower heritability estimates of part lactation yield (120-day milk yield) implied that there may not be any advantage of considering this trait in place of actual 305-day milk yield, whereas, comparable heritability estimates of predicted 305-day milk yield suggested that it could be used for sire evaluation to reduce the cost of milk recording under field conditions.
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Sire Evaluation Using Animal Model and Conventional Methods in Murrah Buffaloes
Jain, A.,Sadana, D.K. Asian Australasian Association of Animal Productio 2000 Animal Bioscience Vol.13 No.9
First lactation records of 683 Murrah buffaloes maintained at National Dairy Research Institute, Karnal, were used for comparing the sire evaluation for age at first calving, first lactation 305-day or less milk yield and first service period. The sires were evaluated using Simple daughters average, Contemporary comparison, Least-squares and BLUP methods. The BLUP evaluations were obtained under single-, two- and three-trait individual animal models. The results revealed that for taking a decision regarding the method of sire evaluation to be used for selecting sires with high breeding values, criteria of the rank correlation could be misleading and comparison of the selected sires is likely to give a veritable picture. The Best Linear Unbiased Prediction method under multi-trait animal model incorporating first lactation milk yield with first service period as a covariable and age at first calving in the model was found to be more efficient and accurate for sire selection in Murrah buffaloes.
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Abarna Ramanathan,John Paul Pearl,Manshi Li,Wang Xiaofeng,Divyajot Sadana,Abhijit Duggal 대한중환자의학회 2021 Acute and Critical Care Vol.36 No.4
Background Atrial fibrillation (AF) of new onset during acute illness (AFNOAI) has a variable incidence of 1%–44% in hospitalized patients. This study assesses the risk factors for persistence of AFNOAI in the 5 years after hospital discharge for critically ill patients. Methods This was a retrospective cohort study. All patients ≥18 years old admitted to the medical intensive care unit (MICU) of a tertiary care hospital from January 1, 2012, to October 31, 2015, were screened. Those designated with AF for the first time during the hospital admission were included. Risk factors for persistent AFNOAI were assessed using a Cox’s proportional hazards model. Results Two-hundred and fifty-one (1.8%) of 13,983 unique MICU admissions had AFNOAI. After exclusions, 108 patients remained. Forty-one patients (38%) had persistence of AFNOAI. Age (hazard ratio [HR], 1.05; 95% confidence interval [CI], 1.01–1.08), hyperlipidemia (HR, 2.27; 95% CI, 1.02–5.05) and immunosuppression (HR, 2.29; 95% CI, 1.02–5.16) were associated with AFNOAI persistence. Diastolic dysfunction (HR, 1.46; 95% CI, 0.71–3.00) and mitral regurgitation (HR, 2.00; 95% CI, 0.91–4.37) also showed a trend towards association with AFNOAI persistence. Conclusions Our study showed that AFNOAI has a high rate of persistence after discharge and that certain comorbid and cardiac factors may increase the risk of persistence. Anticoagulation should be considered, based on a patient’s individual AFNOAI persistence risk.
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Carotid Artery Stenting and Its Impact on Cognitive Function: A Prospective Observational Study
Gupta Avinash N,Bhatti Amit A,Shah Mudasir M,Mahajan Niranjan P,Sadana Divya K,Huded Vikram 대한신경중재치료의학회 2020 Neurointervention Vol.15 No.2
Purpose: Carotid artery stenting (CAS) has evolved as a first-line therapeutic option for carotid revascularization in indicated patients for stroke prevention, but there is still a lack of data on its effect on cognitive function (CF), especially among Indian patients. To determine the effect of CAS on CF and to study the immediate and delayed complications of CAS in Indian patients.Materials and Methods: This was a prospective, observational, single-center study. CF was assessed using Addenbrooke’s cognitive examination version III (ACE) before and 3 months after stenting. The demographic and clinical parameters were also assessed. A follow-up evaluation after 3 months was done to compare CF and to observe the occurrence of any complications.Results: Out of 31 patients, 3 were lost to follow up. There were no immediate or delayed procedure-related complications. There was a statistically significant improvement in overall ACE score and memory before and after stenting. On subgroup analysis of those with and without strokes, there was a significant improvement in visuospatial function and mean ACE score. Those with left CAS had significant improvement in memory, visuospatial, language, and ACE scores than right CAS.Conclusion: CAS was associated with significant improvement in CF in patients.
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Bae, Sang-Hoon,Zhou, Xiaodong,Kim, Seyoung,Lee, Yun Seog,Cruz, Samuel S.,Kim, Yunjo,Hannon, James B.,Yang, Yang,Sadana, Devendra K.,Ross, Frances M.,Park, Hongsik,Kim, Jeehwan National Academy of Sciences 2017 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.114 No.16
<P>Graphene epitaxy on the Si face of a SiC wafer offers monolayer graphene with unique crystal orientation at the wafer-scale. However, due to carrier scattering near vicinal steps and excess bilayer stripes, the size of electrically uniform domains is limited to the width of the terraces extending up to a few microns. Nevertheless, the origin of carrier scattering at the SiC vicinal steps has not been clarified so far. A layer-resolved graphene transfer (LRGT) technique enables exfoliation of the epitaxial graphene formed on SiC wafers and transfer to flat Si wafers, which prepares crystallographically single-crystalline monolayer graphene. Because the LRGT flattens the deformed graphene at the terrace edges and permits an access to the graphene formed at the side wall of vicinal steps, components that affect the mobility of graphene formed near the vicinal steps of SiC could be individually investigated. Here, we reveal that the graphene formed at the side walls of step edges is pristine, and scattering near the steps is mainly attributed by the deformation of graphene at step edges of vicinalized SiC while partially from stripes of bilayer graphene. This study suggests that the two-step LRGT can prepare electrically single-domain graphene at the wafer-scale by removing the major possible sources of electrical degradation.</P>
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