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Ghanbari, Ali,Khalilpasha, Abbas,Sabermahani, Mohsen,Heydari, Babak Techno-Press 2013 Geomechanics & engineering Vol.5 No.2
Calculation of seismic displacements in reinforced slopes plays a crucial role in appropriate design of these structures however current analytical methods result indifferent values for permanent displacements of the slope. In this paper, based on limit equilibrium and using the horizontal slices method, a new formulation has been proposed for estimating the seismic displacements of a reinforced slope under earthquake records. In this method, failure wedge is divided into a number of horizontal slices. Assuming linear variations for tensile forces of reinforcements along the height of the slope, the coefficient of yield acceleration has been estimated. The simplicity of calculations and taking into account the frequency content of input triggers are among the advantages of the present formulation. Comparison of the results shows that the yield acceleration calculated by the suggested method is very close to the values resulted from other techniques. On the other hand, while there is a significant difference between permanent displacements, the values obtained from the suggested method place somehow between those calculated by the other techniques.
Markov's Modeling for Screening Strategies for Colorectal Cancer
Barouni, Mohsen,Larizadeh, Mohammad Hassan,Sabermahani, Asma,Ghaderi, Hossien Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Economic decision models are being increasingly used to assess medical interventions. Advances in this field are mainly due to enhanced processing capacity of computers, availability of specific software to perform the necessary tasks, and refined mathematical techniques. We here estimated the incremental cost-effectiveness of ten strategies for colon cancer screening, as well as no screening, incorporating quality of life, noncompliance and data on the costs and profit of chemotherapy in Iran. We used a Markov model to measure the costs and quality-adjusted life expectancy of a 50-year-old average-risk Iranian without screening and with screening by each test. In this paper, we tested the model with data from the Ministry of Health and published literature. We considered costs from the perspective of a health insurance organization, with inflation to 2011, the Iranian Rial being converted into US dollars. We focused on three tests for the 10 strategies considered currently being used for population screening in some Iranians provinces (Kerman, Golestan Mazandaran, Ardabil, and Tehran): low-sensitivity guaiac fecal occult blood test, performed annually; fecal immunochemical test, performed annually; and colonoscopy, performed every 10 years. These strategies reduced the incidence of colorectal cancer by 39%, 60% and 76%, and mortality by 50%, 69% and 78%, respectively, compared with no screening. These approaches generated ICER (incremental cost-effectiveness ratios) of $9067, $654 and $8700 per QALY (quality-adjusted life year), respectively. Sensitivity analyses were conducted to assess the influence of various scales on the economic evaluation of screening. The results were sensitive to probabilistic sensitivity analysis. Colonoscopy every ten years yielded the greatest net health value. Screening for colon cancer is economical and cost-effective over conventional levels of WTP8.
Blood Malignancies in Mazandaran Province of Iran
Tahmasby, Bahram,Marnani, Ahmad Barati,Maleki, Mohammadreza,Barouni, Mohsen,Mousavi, Seyyed Hamid,Naseriyan, Behjat,Nazarnezhad, Mirzaali,Alizadeh, Ali,Sabermahani, Asma Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Background: Leukemia and lymphoma demonstrate significantly incidence rates throughout the world and particularly in Iran they cause serious mortality and diagnosis and treatment expenditures for both families and the health system. Combined they account for about 11 percent of cancers in Mazandaran province, ranking number 2 in prevalent cancers. The purpose of this study was to provide a first general and specific description of leukemia and lymphoma in Mazandaran province. Materials and Methods: In this descriptive retrospective study, entire patient's data were reviewed which had confirmed diagnosis of leukemia and lymphoma with valid laboratory or pathology reports in the period 2001-2008. The data were collected by Babol health research site related to Tehran University of Medical Science. Incidence rates based on age groups, gender, city of residence and type of malignancy were calculated and analyzed. Results: In Mazandaran province, 1,146 cases of leukemia and lymphoma were encountered, 5.9 in 100,000 persons on average annually. The highest incidence rates were obtained at age of 70 or above (26.4) and the lowest at age of 0-9 (2.3).The incidence rates in males and females were 7.1 and 4.8 respectively with a ratio of 1.5. The highest incidence rate was in Babol (7.3) and the lowest was calculated in Neka and Tonekabon equally (1.5). According to the type of malignancy, non Hodgkin lymphoma, with 2.5/100,000 have the most incidence rate and myeloid leukemia with 1.8 had the lowest. Conclusions: The obtained findings indicate clear differences in incidence rates based on age, gender, residence, and type of malignancy. Therefore it's suggested that in addition to promote data collecting programs, research projects should be programmed to define leukemia and lymphoma risk factors in this province.