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Takafumi Mie,Takashi Sasaki,Ryo Kanata,Takaaki Furukawa,Tsuyoshi Takeda,Akiyoshi Kasuga,Masato Matsuyama,Masato Ozaka,Naoki Sasahira 대한소화기내시경학회 2021 Clinical Endoscopy Vol.54 No.5
Background/Aims: Several fine-needle biopsy (FNB) needles are available for endoscopic ultrasound (EUS)-guided tissueacquisition. However, there is disagreement on which type of needle has the best diagnostic yield. The aim of this study was tocompare the performance and safety of two commonly used EUS-FNB needles. Methods: We retrospectively analyzed consecutive patients who underwent EUS-FNB between June 2016 and March 2020 in ourhospital. Two types of needles were evaluated: a 20-gauge Menghini needle with a lateral forward bevel and a 22-gauge Franseenneedle. Rapid on-site evaluation was performed in all the cases. A multivariate analysis was performed to clarify the negativepredictive factors for obtaining a histological diagnosis. Propensity score matching was performed to compare the diagnostic yieldsof these two needles. Results: We analyzed 666 patients and 690 lesions. The overall diagnostic rate of histology alone was 88.8%, and the overall adverseevent rate was 1.5%. Transduodenal access and small lesions (≤2 cm) were identified as negative predictive factors for obtaining ahistological diagnosis. After propensity score matching, 482 lesions were analyzed. The diagnostic accuracy rates of histology in theM and F needle groups were 89.2% and 88.8%, respectively (p=1.00). Conclusions: Both the needles showed high diagnostic yield, and no significant difference in performance was observed between thetwo.