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Tomohiko Kiriyama,Rumi Tanemura,Yoshihiro Nakamura,Chiaki Takemoto,Mariko Hashimoto,Hirohiko Utsumi 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.8
Objective Substantial research has revealed cognitive function impairments in patients with major depressive disorder (MDD). However, the relationship between MDD cognitive function impairment and brain activity is yet to be elucidated. This study aimed to reveal this relationship using near-infrared spectroscopy (NIRS) to extensively measure frontotemporal cortex function. Methods We recruited 18 inpatients with MDD and 22 healthy controls. Regional oxygenated hemoglobin changes (oxy-Hb) were measured during a verbal fluency task and its relationship to cognitive function was assessed. Cognitive function was assessed using the Japanese version of the Brief Assessment of Cognition in Schizophrenia. Results Compared to healthy controls, patients with MDD displayed poorer motor speed, attention and speed of information processing, and executive function. In the bilateral prefrontal and temporal surface regions, regional oxy-Hb changes were significantly lower in patients with MDD than in healthy individuals. Moreover, we observed a correlation between reduced activation in the left temporal region and poor motor speed in patients with MDD. Conclusion We suggest that reduced activation in the left temporal region in patients with MDD could be a biomarker of poor motor speed. Additionally, NIRS may be useful as a noninvasive, clinical measurement tool for assessing motor speed in these patients.
Evaluation of Simplified Repeated Resistance Training System for Severe Hemiplegic Stroke Patient
Michito Yasukita,Yuki Iida,Kazunori Yamazaki,Noritaka Sato,Yoshifumi Morita,Hiroyuki Ukai,Yoshiaki Takagi,Yoshitaka Aoki,Hirofumi Tanabe,Rumi Tanemura 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10
We have developed a three-dimensional force display robot (3D robot) to discover and embody needs in rehabilitation site. Then we have exchanged opinions with therapists by using the 3D robot together in rehabilitation site. From a therapist" needs we have developed repeated resistance training system by using the 3D robot as one of the application of the 3D robot. On the basis of the results we have developed a simplified repeated resistance training system equipped with a user interface for easy operation for therapists. Moreover, we have developed a brace for fixation as the attachment between the training system and the patient’s arm. In this paper, we perform the functional evaluation of the simplified repeated resistance training system and the brace in the clinical site. These results are based on the opinions from the therapist and the patient. Moreover, we verify the therapeutic effects of the repeated resistance training using the simplified system for a hemiplegic stroke patient. The AROMs of pronation and supination of the patient were improved after repeated resistance training using the simplified system.