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- 저자 : Rosiane Mattar (검색결과 2 건)
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Nathalie Jeanne Bravo-Valenzuela,Alberto Borges Peixoto,Rosiane Mattar,Edward Araujo Júnior 한국심초음파학회 2022 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.30 No.2
BACKGROUND: To assess the interventricular septum (IVS) volume of fetuses from pre-gestational diabetes mellitus (DM) pregnant women by 3-dimensional ultrasound using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL) methods. METHODS: This was a prospective cross-sectional study of 45 fetuses from pre-gestational DM and 45 fetuses from healthy pregnant women (controls). Only singleton pregnancies between 20 and 34 + 6 weeks of gestation were included. The fetal IVS volumes were obtained off-line using STIC and VOCAL methods. To analyze differences among variables, the Student’s t-test and Mann-Whitney U test were used. The correlation among continuous variables was determine using Spearman’s correlation test (r). RESULTS: The median of fetal IVS volume was significantly higher in pre-gestational DM than in healthy pregnant women (0.3 cm3 vs. 0.2 cm3, p = 0.032). A strong positive correlation was observed between fetal IVS volume and gestational age at the time of ultrasound examination (r = 0.75, R2 = 0.48, p < 0.0001) and between fetal IVS volume and estimated fetal weight (r = 0.63, R2 = 0.37, p < 0.0001). No significant correlation was noted between fetal IVS volume and glycated hemoglobin levels (r = −0.16, R2 = 0.01, p = 0.540) in the pre-gestational DM pregnant women. CONCLUSIONS: Significant differences were observed in fetal IVS volumes between pre-gestational and healthy mothers, with higher values in the fetuses of pre-gestational DM pregnant women.
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Nathalie Jeanne Magioli Bravo-Valenzuela,Alberto Borges Peixoto,Rosiane Mattar,Edward Araujo Júnior 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.3
ObjectiveTo assess the mitral and tricuspid annular plane systolic excursions (MAPSE and TAPSE, respectively) and cardiacoutput (CO) in fetuses of pregnant women with pregestational diabetes mellitus (DM) using spatio-temporal imagecorrelation M-mode (STIC-M) and virtual organ computer-aided analysis (VOCAL). MethodsThis study was prospective and cross-sectional. It included 45 fetuses each from mothers with pregestational DMand healthy mothers, with gestation ages ranging from 20 to 36.6 weeks. The fetal cardiac volumes were obtainedand analyzed by STIC and VOCAL methods. MAPSE and TAPSE were measured by STIC-M in the apical or basal fourchamberview. The values of the right (RV) and left ventricular (LV) CO were calculated by STIC and VOCAL. ResultsThe median values of TAPSE were 6.1 and 6.2 mm in the diabetic and control groups (P<0.001), respectively. The medianvalues of MAPSE were 4.6 mm in the fetuses of mothers with diabetes and 4.8 mm in fetuses of healthy mothers. The fetal LV CO (60.4 L/min vs. 71.1 L/min; P=0.033, respectively) and RV CO (65.2 vs. 70.1 L/min; P=0.026, respectively)were lower in the pregestational DM group than in the control group. A significant effect of pregestational DM wasobserved in all functional parameters after adjusting, with fetal heart rate as covariant. There was moderate significantpositive correlation between MAPSE and LV CO (r=0.53; P=0.0001) and between TAPSE and RV CO (r=0.46; P=0.0001). ConclusionSignificant difference in functional parameters (TAPSE, MAPSE and LV CO) obtained by STIC and VOCAL wereobserved in the fetuses of the pregestational DM group compared to those of the control group.
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