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Zhe Cao,Qiyu Huang,Chuanrui Zhao,Qing Zhang 대한금속·재료학회 2016 ELECTRONIC MATERIALS LETTERS Vol.12 No.6
Metal-assisted chemical etching (MACE) has been used as a promising alternativemethod to fabricate micro/nano-structures on silicon substrates inexpensively. In thispaper, profiles of deep trenches on silicon substrates, with different doping levels,fabricated by MACE were studied. A layer of interconnected gold islands was firstdeposited onto the silicon substrate as catalyst. Electrochemical etching was thenperformed in a hydrofluoric acid (HF) and hydrogen peroxide (H2O2) mixturesolution with different HF-to-H2O2 ratio ρ (ρ = [HF]/([HF] + [H2O2])). Vertical deeptrenches were fabricated successfully by using this method. It was observed thateven under identical experimental condition, sidewalls with various tilting anglesand different morphology could still form on silicon substrates with differentresistivity. This possibly because with different resistivity silicon substrate, thegradient of holes in it greatly changed, and so did the final morphology. As a result,the tilting angle of etched trench sidewall can be tuned from 6 ° to 96 ° using siliconsubstrates with different resistivity and etchants with different ρ. By applying theangle-tuning technique revealed in this study, high aspect ratio patterns with verticalsidewalls could be fabricated and three-dimensional complex structures could bedesigned and realized in the future.
Qianqian Shan,Shengsheng Li,Qiyu Cao,Chenglong Yue,Mingshan Niu,Xiangyu Chen,Lin Shi,Huan Li,Shangfeng Gao,Jun Liang,Rutong Yu,Xuejiao Liu 대한생리학회-대한약리학회 2020 The Korean Journal of Physiology & Pharmacology Vol.24 No.3
Chromosomal region maintenance 1 (CRM1) is associated with an adverse prognosis in glioma. We previously reported that CRM1 inhibition suppressed glioma cell proliferation both in vitro and in vivo. In this study, we investigated the role of CRM1 in the migration and invasion of glioma cells. S109, a novel reversible selective inhibitor of CRM1, was used to treat Human glioma U87 and U251 cells. Cell migration and invasion were evaluated by wound-healing and transwell invasion assays. The results showed that S109 significantly inhibited the migration and invasion of U87 and U251 cells. However, mutation of Cys528 in CRM1 abolished the inhibitory activity of S109 in glioma cells. Furthermore, we found that S109 treatment decreased the expression level and activity of MMP2 and reduced the level of phosphorylated STAT3 but not total STAT3. Therefore, the inhibition of migration and invasion induced by S109 may be associated with the downregulation of MMP2 activity and expression, and inactivation of the STAT3 signaling pathway. These results support our previous conclusion that inhibition of CRM1 is an attractive strategy for the treatment of glioma.
Compound-Type Hybrid Energy Storage System and Its Mode Control Strategy for Electric Vehicles
Wang, Bin,Xu, Jun,Cao, Binggang,Li, Qiyu,Yang, Qingxia The Korean Institute of Power Electronics 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.3
This paper proposes a novel compound-type hybrid energy storage system (HESS) that inherits the unique advantages of both battery/supercapacitor (SC) and the SC/battery HESSs for electric vehicles (EVs). Eight operation modes are designed to match this system. A mode control strategy is developed for this HESS on the basis of these modes, and five classes of operation modes are established to simplify this strategy. The mode control strategy focuses on high operating efficiency and high power output. Furthermore, the compound-type HESS is designed such that the SC is the main priority in braking energy absorption. Thus, this HESS can operate efficiently and extend battery life. Simulation results also show that the compound-type HESS can not only supply adequate power to the motor inverter but can also determine suitable operation modes in corresponding conditions. Experimental results demonstrate that this HESS can extend battery life as well. The overall efficiency of the compound-type HESS is higher than those of the battery/SC and the SC/battery HESSs.
Compound-Type Hybrid Energy Storage System and Its Mode Control Strategy for Electric Vehicles
Bin Wang,Jun Xu,Binggang Cao,Qiyu Li,Qingxia Yang 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.3
This paper proposes a novel compound-type hybrid energy storage system (HESS) that inherits the unique advantages of both battery/supercapacitor (SC) and the SC/battery HESSs for electric vehicles (EVs). Eight operation modes are designed to match this system. A mode control strategy is developed for this HESS on the basis of these modes, and five classes of operation modes are established to simplify this strategy. The mode control strategy focuses on high operating efficiency and high power output. Furthermore, the compound-type HESS is designed such that the SC is the main priority in braking energy absorption. Thus, this HESS can operate efficiently and extend battery life. Simulation results also show that the compound-type HESS can not only supply adequate power to the motor inverter but can also determine suitable operation modes in corresponding conditions. Experimental results demonstrate that this HESS can extend battery life as well. The overall efficiency of the compound-type HESS is higher than those of the battery/SC and the SC/battery HESSs.