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Synthesis of Ag/TiO<sub>2</sub> Core/Shell Nanoparticles with Antibacterial Properties
Lin, Yue,Qiqiang, Wang,Xiaoming, Zhang,Zhouping, Wang,Wenshui, Xia,Yuming, Dong Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.8
Monodispersed Ag/$TiO_2$ core/shell nanoparticles were synthesized in solution via colloid-seeded deposition process using Ag nanoparticles as colloid seeds and $Ti(SO_4)_2$ as Ti-source respectively. Silver nitrate was reduced to Ag nanoparticles with $N_2H_4{\cdot}H_2O$ in the presence of CTAB as stabilizing agent. The titania sols hydrolyzed by the $Ti(SO_4)_2$ solution deposited on the surface of Ag nanoparticles to form the Ag/$TiO_2$ core/shell nanoparticles. Inductively coupled plasma atomic emission spectrometry (ICP-AES) showed low amount of Ag ion leaching from the Ag/$TiO_2$ core/shell nanoparticles. The Ag/$TiO_2$ core/shell nanoparticles indicated excellent antibacterial effects against Escherichia coli and maintained long-term antibacterial property.
( Jiaofen Nan ),( Liangliang Zhang ),( Qiqiang Chen ),( Nannan Zong ),( Peiyong Zhang ),( Xing Ji ),( Shaohui Ma ),( Yuchen Zhang ),( Wei Huang ),( Zhongzhou Du ),( Yongquan Xia ),( Ming Zhang ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2018 Journal of Neurogastroenterology and Motility (JNM Vol.24 No.1
Background/Aims The Rome III criteria separated chronic constipation into functional constipation (FC) and constipation-predominant irritable bowel syndrome (IBS-C), but some researchers questioned the partitioning and treated both as distinct parts of a continuum. The study aims to explore the similarity and diversity of brain white matter between FC and IBS-C. Methods The voxel-wise analysis of the diffusion parameters was used to quantify the white matter changes of female brains in 18 FC patients and 20 IBS-C patients compared with a comparison group with 19 healthy controls by tract-based spatial statistics. The correlations between diffusive parameters and clinical symptoms were evaluated using a Pearson’s correlation. Results In comparison to healthy controls, FC patients showed a decrease of fractional anisotropy (FA) and an increase of radial diffusivity (RD) in multiple major fibers encompassing the corpus callosum (CC, P = 0.001 at peak), external capsule (P = 0.002 at peak), corona radiata (CR, P = 0.001 at peak), and superior longitudinal fasciculus (SLF, P = 0.002 at peak). In contrast, IBS-C patients showed FA and RD aberrations in the CC (P = 0.048 at peak). Moreover, the direct comparison between FC and IBS-C showed only RD differences in the CR and SLF. In addition, FA and RD in the CC were significantly associated with abdominal pain for all patients, whereas FA in CR (P = 0.016) and SLF (P = 0.040) were significantly associated with the length of time per attempt and incomplete evacuation separately for FC patients. Conclusion These results may improve our understanding of the pathophysiological mechanisms underlying different types of constipation. (J Neurogastroenterol Motil 2018;24:107-118)
Synthesis of Ag/TiO_2 Core/Shell Nanoparticles with Antibacterial Properties
Yue Lin,Wang Qiqiang,Zhang Xiaoming,Wang Zhouping,Xia Wenshui,Dong Yuming 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.8
Monodispersed Ag/TiO_2 core/shell nanoparticles were synthesized in solution via colloid-seeded deposition process using Ag nanoparticles as colloid seeds and Ti(SO_4)_2 as Ti-source respectively. Silver nitrate was reduced to Ag nanoparticles with N_2H_4·H_2O in the presence of CTAB as stabilizing agent. The titania sols hydrolyzed by the Ti(SO_4)_2 solution deposited on the surface of Ag nanoparticles to form the Ag/TiO_2 core/shell nanoparticles. Inductively coupled plasma atomic emission spectrometry (ICP-AES) showed low amount of Ag ion leaching from the Ag/TiO_2 core/shell nanoparticles. The Ag/TiO_2 core/shell nanoparticles indicated excellent antibacterial effects against Escherichia coli and maintained long-term antibacterial property.
Road Damage Detection and Classification based on Multi-level Feature Pyramids
( Junru Yin ),( Jiantao Qu ),( Wei Huang ),( Qiqiang Chen ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.2
Road damage detection is important for road maintenance. With the development of deep learning, more and more road damage detection methods have been proposed, such as Fast R-CNN, Faster R-CNN, Mask R-CNN and RetinaNet. However, because shallow and deep layers cannot be extracted at the same time, the existing methods do not perform well in detecting objects with fewer samples. In addition, these methods cannot obtain a highly accurate detecting bounding box. This paper presents a Multi-level Feature Pyramids method based on M2det. Because the feature layer has multi-scale and multi-level architecture, the feature layer containing more information and obvious features can be extracted. Moreover, an attention mechanism is used to improve the accuracy of local boundary boxes in the dataset. Experimental results show that the proposed method is better than the current state-of-the-art methods.
Yang, Jianjun,Yuan, Donghong,Xing, Tongchao,Su, Hongli,Zhang, Shengjun,Wen, Jiansheng,Bai, Qiqiang,Dang, Dongmei The Korean Society of Ginseng 2016 Journal of Ginseng Research Vol.40 No.4
Background: Ginsenoside Rh2 (GRh2) is the main bioactive component in American ginseng, a commonly used herb, and its antitumor activity had been studied in previous studies. PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK), a serine/threonine protein kinase, is highly expressed in HCT116 colorectal cancer cells. Methods: We examined the effect of GRh2 on HCT116 cells ex vivo. Next, we performed in vitro binding assay and in vitro kinase assay to search for the target of GRh2. Furthermore, we elucidated the underlying molecular mechanisms for the antitumor effect of GRh2 ex vivo and in vivo. Results: The results of our in vitro studies indicated that GRh2 can directly bind with PBK/TOPK and GRh2 also can directly inhibit PBK/TOPK activity. Ex vivo studies showed that GRh2 significantly induced cell death in HCT116 colorectal cancer cells. Further mechanistic study demonstrated that these compounds inhibited the phosphorylation levels of the extracellular regulated protein kinases 1/2 (ERK1/2) and (H3) in HCT116 colorectal cancer cells. In vivo studies showed GRh2 inhibited the growth of xenograft tumors of HCT116 cells and inhibited the phosphorylation levels of the extracellular regulated protein kinases 1/2 and histone H3. Conclusion: The results indicate that GRh2 exerts promising antitumor effect that is specific to human HCT116 colorectal cancer cells through inhibiting the activity of PBK/TOPK.