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        Influence of Pore Structure Characteristics on the Mechanical and Durability Behavior of Pervious Concrete Material Based on Image Analysis

        Ruyan Liu,Yin Chi,Shengyun Chen,Qinghui Jiang,Xiaoyu Meng,Kun Wu,Shengjia Li 한국콘크리트학회 2020 International Journal of Concrete Structures and M Vol.14 No.4

        Pervious concrete has been widely used in parking lots and other lightweight streets. Performances of pervious concrete are strongly dependent on its pore structure characteristics. This paper investigates the relationship among porosity, permeability, compressive strength, durability and the pore structure characteristics of pervious concrete. The influences of basalt fiber and fine aggregate on the pervious concrete are also discussed. Pervious concrete specimens with different pore structures were prepared by combining basalt aggregate with size of 5-10 mm and 10-15 mm at different proportion. The pore structure characteristics such as area porosity, pore sizes, and pore distribution of pervious concrete were obtained and analyzed using image analysis method. Experimental results showed that the pore structure characteristics of pervious concrete have effects on its mechanical and durability behaviors. Homogeneous pore distribution and large distances between pores increase the compressive strength and improve freeze-thaw durability of pervious concrete. Due to the difference in the internal pore structure of pervious concretes, specimens with similar volumetric porosities had different permeability coefficients. A series of numerical models were regenerated through a MATLAB code using pore structural parameters derived from the image analysis method, then the numerical models were fed to ANSYS for meshing and further simulation. The comparison of the simulation and experimental results showed close accuracy, which verified the applied simulation analysis method based on image analysis technology.

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        Comparison of Six Automated Immunoassays With Isotope-Diluted Liquid Chromatography–Tandem Mass Spectrometry for Total Thyroxine Measurement

        Songlin Yu,Weiyan Zhou,Xinqi Cheng,Qinghui Meng,Honglei Li,Li’an Hou,Jun Lu,Shaowei Xie,Qian Cheng,Chuanbao Zhang,Ling Qiu 대한진단검사의학회 2019 Annals of Laboratory Medicine Vol.39 No.4

        Background: Accurate serum total thyroxine (TT4) measurement is important for thyroid disorder diagnosis and management. We compared the performance of six automated immunoassays with that of isotope-diluted liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS) as the reference method. We also evaluated the correlation of thyroid stimulating hormone (TSH) with TT4 measured by ID-LC-MS/MS and immunoassays. Methods: Serum was collected from 156 patients between October 2015 and January 2016. TT4 was measured by immunoassays from Abbott (Architect), Siemens (ADVIA Centaur XP), Roche (E601), Beckman-Coulter (Dxi800), Autobio (Autolumo A2000), and Mindray (CL-1000i), and by ID-LC-MS/MS. Results were analyzed using Passing–Bablok regression and Bland–Altman plots. Minimum requirements based on biological variation were as follows: a mean bias of ≤4.5% and total imprecision (CV) of ≤3.7%. Results: All immunoassays showed a correlation >0.945 with ID-LC-MS/MS; however, the slope of the Passing–Bablok regression line varied from 0.886 (Mindray) to 1.23 (Siemens) and the intercept from -12.8 (Siemens) to 4.61 (Mindray). Only Autobio, Beckman-Coulter, and Roche included the value of one in the 95% confidence interval for slope. The mean bias ranged from -10.8% (Abbott) to 9.0% (Siemens), with the lowest value noted for Roche (3.5%) and the highest for Abbott (-10.8%). Only Abbott and Roche showed within-run and total CV ≤3.7%. Conclusions: Though all immunoassays correlated strongly with ID-LC-MS/MS, most did not meet the minimum clinical requirement. Laboratories and immunoassay manufacturers must be aware of these limitations.

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