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- 저자 : Priyanka Goswami (검색결과 2 건)
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Methyl Red: A Fluorescent Sensor for Hg2+ over Na+, K+, Ca2+, Mg2+, Zn2+, and Cd2+
Diganta Kumar Das,Priyanka Goswami,Champa Barman,Biva Das 대한환경공학회 2012 Environmental Engineering Research Vol.17 No.-
Methyl red (MR), a very well known acid base indicator (pKa = 5.2), shows fluorescence emission in the range 320 nm to 480 nm, with an emission maximum at 375 nm on excitation by photons at 310 nm. A fluorescent intensity titration of MR by Hg2+ ion, a well known toxic heavy metal ion, shows quenching of the fluorescent intensity of MR. The quenching continues till the concentration ratio between MR and Hg2+ ion becomes 1:1. Similar titration with a number of other metal ions, namely Na+, K+, Ca2+, Mg2+, Zn2+, and Cd2+, has very small effect on the fluorescent intensity of MR. Thus MR acts as a selective fluorescent sensor for Hg2+ ion by selective fluorescence quenching. The efficiency of fluorescence quenching value is found to be 8.0. The binding ratio and binding constant (β) between MR and Hg2+ ion are calculated from the fluorescence and UV/visible spectral data, and are found to be 1:1 and log β =4.68. The Hg:MR complex was found to be stable in the pH range 5.5 to 8.2.
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Anthelmintic and Analgesic Activities of Trachyspermum Khasianum H. Wolff
Sutnga, Innocent,Marbaniang, Balari,Hazarika, Gautom,Goswami, Priyanka,Choudhury, Ananta KOREAN PHARMACOPUNCTURE INSTITUTE 2020 Journal of pharmacopuncture Vol.23 No.4
Objectives: Trachyspermum khasianum H. Wolff is a rare medicinal plant characteristically used by the traditional healers in traditional medicine for the treatment of throat-pain, toothache, and stomach ache. The study was designed to determine the anthelmintic and analgesic properties of the aerial parts of Trachyspermum khasianum H. Wolff (Family: Apiaceae). The aqueous and ethanol extract of T. khasianum H. Wolff was prepared and subjected for evaluation to determine the possible therapeutic effects. Methods: Anthelmintic activities of the extracts were determined by observing the time taken to paralyze and the time taken for the death of earthworms (Eisenia foetida) as compared to the standard drug-Albendazole (20 mg/ml) and control. Analgesic potential of the extracts was evaluated using Eddy's hot plate method to understand the analgesic activity in rats (Wistar rats) at 100 mg/kg and 200 mg/kg body weight doses and compared with the standard reference (Diclofenac sodium: 10 mg/kg of animals). Results: The extracts showed a significant dose-dependent anthelmintic effect at the different concentrations (10, 20, and 40) mg/ml, compared to that of the standard drug (20 mg/ml). Also, the results suggested that the plant extracts possess significantly analgesic activity in rats. Conclusion: The studies indicate that Trachyspermum khasianum shows anthelmintic and potent analgesic activities. Further research should be carried out to identify the specific phytoconstituents responsible for both analgesic and anthelmintic activities and its possible mechanism of action.
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