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        Discharge Coefficient and Energy Dissipation over Stepped Spillway under Skimming Flow Regime

        Hossein Shahheydari,Ehsan Jafari Nodoshan,Reza Barati,Mehdi Azhdary Moghadam 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.4

        Stepped spillways have a wide range of applicability as a hydraulic structure in large dams to dissipate energy of high-velocity flows at a downstream area of dams as well as release overflows into the downstream. In this study, the numerical simulation of the flow over the stepped spillway was investigated by using Flow3D software as an analytic flow field. The RNG k-ε model was applied as the turbulence model, and Volume of Fluid (VOF) model was used to determine the free surface flow profiles. At the first stage, the model was verified by reliable experimental data. Then, in order to investigate the various features of skimming flow regime, 112 numerical spillway models was designed, which 96 models were stepped spillway models and 16 models were smooth spillway models (i.e., WES profile). In these numerical experiment, two step sizes, six configuration, four passing discharge and four profile slopes (15, 30, 45 and 60 degrees) with various relative discharges were considered to investigate the energy dissipation and discharge coefficient rates. The results indicated that discharge coefficient rate and energy dissipation rate have inverse relationship. Also it was observed that when relative discharges increased, energy dissipation rate decreased and discharge coefficient rate increased.

      • Evaluation of Human Papillomavirus Infections in Prostatic Disease: a Cross-Sectional Study in Iran

        Ghasemian, Ehsan,Monavari, Seyed Hamid Reza,Irajian, Gholam Reza,Nodoshan, Mohammad Reza Jalali,Roudsari, Rouhollah Vahabpour,Yahyapour, Yousef Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        Background: The role of inflammation in prostate diseases is suggested by the presence of inflammatory cells within the prostate in benign prostatic hyperplasia (BPH) and prostate cancer (PCa) patients. In addition, bacterial and viral infection may lead to chronic and recurrent inflammation of the prostate. The human papillomaviruses (HPVs) are a family of sexually transmitted viruses which have been implicated in the aetiology of cervical cancer and several other malignancies. This study evaluated the frequency of HPV infection in individuals with prostatic disease in Iran. Materials and Methods: The study included formalin fixed paraffin- embedded tissue samples of 196 primary prostate cases, including 29 PCa and 167 BPH samples. HPV DNA was purified and amplified through MY09/MY11 and GP5+/GP6+ primers with nested PCR. All patients were interviewed using a questionnaire to collect demographic information. Results: Nested PCR showed that HPV DNA was found in 17.2 percent of PCa samples and 4.8 percent of BPH samples (not significant). Conclusions: Our data do not support a significant role of HPV infection in prostatic disease in Iranian patients, but demographic data indicated a probable association between presence of HPV DNA and risk of inflammation in prostate tissue which might lead to prostate carcinoma. Further studies are required to elucidate any roles of HPV infection in prostatic disease.

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