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TWO-SWITCH BOOST CHOPPER-BASED PFC RECTIFIER FOR ELECTRONIC BALLAST
Nobuo TAKAHASHI,Yoshito KATO,Masaaki OHKITA,Kenzo OKUTSU,Makoto MATSUYAMA,Mutsuo NAKAOKA 전력전자학회 1998 ICPE(ISPE)논문집 Vol.- No.-
This paper presents a two-switch boost chopper with a sinewave current shaping and power factor correction scheme, which is applied for driving electronic ballast using high frequency resonant inverter.<br/> A working principle of the proposed one-converter type electronic ballast with power factor correction and active filtering schemes is described on the bases of the equivalent circuit of each operation mode, together with operation analysis. The steady-state performance evaluations of this electronic ballast are illustrated and discussed in experiment.<br/>
Risk Factors for Acute Cholangitis Caused by Enterococcus faecalis and Enterococcus faecium
( Yuki Karasawa ),( Jun Kato ),( Satoshi Kawamura ),( Kentaro Kojima ),( Takamasa Ohki ),( Michiharu Seki ),( Kazumi ),( Tagawa ),( Nobuo Toda ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2021 Gut and Liver Vol.15 No.4
Background/Aims: Acute cholangitis (AC) is a potentially life-threatening bacterial infection, and timely antimicrobial treatment, faster than that achieved with bacterial cultures, is recommended. Although the current guidelines refer to empirical antimicrobial treatment, various kinds of antimicrobial agents have been cited because of insufficient analyses on the spectrum of pathogens in AC. Enterococcus spp. is one of the most frequently isolated Gram-positive bacteria from the bile of patients with AC, but its risk factors have not been extensively studied. This study aimed to analyze the risk factors of AC caused by Enterococcus faecalis and Enterococcus faecium. Methods: Patients with AC who were hospitalized in a Japanese tertiary center between 2010 and 2015 were retrospectively analyzed. Patients’ first AC episodes in the hospital were evaluated. Results: A total of 266 patients with AC were identified. E. faecalis and/or E. faecium was isolated in 56 (21%) episodes of AC. Prior endoscopic sphincterotomy (EST), the presence of a biliary stent, prior cholecystectomy, and past intensive care unit admission were more frequently observed in AC patients with E. faecalis and/or E. faecium than in those without such bacteria. Prior EST was identified as an independent risk factor for AC caused by E. faecalis and/or E. faecium in the multivariate analysis. Conclusions: Given the intrinsic resistance of E. faecalis and E. faecium to antibiotics, clinicians should consider empirical therapy with anti-enterococcal antibiotics for patients with prior EST. (Gut Liver 2021;15:616-624)
Expression of Hyaluronidase-4 in a Rat Spinal Cord Hemisection Model
Yoshiyuki Tachi,Tetsuhito Okuda,Norio Kawahara,Nobuo Kato,Yasuhito Ishigaki,Tadami Matsumoto 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.1
Study Design: Examination of hyaluronidase-4 (Hyal-4) expression in a rat spinal cord hemisection model. Purpose: To determine the status of Hyal-4 expression after hemisection of the spinal cord, and the relationship between its expression and that of chondroitin sulfate proteoglycans (CSPGs). Overview of Literature: CSPGs are expressed at the site of spinal cord injury and inhibit axon regeneration. Administration of exogenous chrondroitinase ABC (ChABC), derived from bacteria, digested CSPGs and promoted axonal regrowth. Using a rat hemisection model, we have demonstrated peak CSPGs levels at by 3 weeks after injury but then decreased spontaneously. Could there be an endogenous enzyme similar to ChABC in the spinal cord? It has been suggested that Hyal-4 is involved in CSPG degradation. Methods: A rat hemisection model was prepared and spinal cord frozen sections were prepared at 4 days and 1, 2, 3, 4, 5, and 6 weeks post-cordotomy and stained for CSPGs and Hyal-4 and subjected to Western blotting. Results: CSPGs appeared at the injury site at 4 days after hemisection, reached a peak after 3 weeks, and then decreased. Hyal-4 was observed around the injury site from 4 days after cordotomy and increased until after 5–6 weeks. Double staining showed Hyal-4 around CSPGs. Western blotting identified a band corresponding to Hyal-4 from 4 days after hemisection. Conclusions: Hyal-4 was expressed in a rat hemisection model in areas surrounding CSPGs, and as its peak was delayed compared with that of CSPGs. These results suggest the involvement of Hyal-4 in the digestion of CSPGs.