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      저자 : Nathalie Jeanne Magioli Bravo-Valenzuela (검색결과 1 건)
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        Fetal cardiac function by mitral and tricuspid annular plane systolic excursion using spatio-temporal image correlation M‐mode and left cardiac output in fetuses of pregestational diabetic mothers

        Nathalie Jeanne Magioli Bravo-Valenzuela,Alberto Borges Peixoto,Rosiane Mattar,Edward Araujo Júnior 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.3

        ObjectiveTo assess the mitral and tricuspid annular plane systolic excursions (MAPSE and TAPSE, respectively) and cardiacoutput (CO) in fetuses of pregnant women with pregestational diabetes mellitus (DM) using spatio-temporal imagecorrelation M-mode (STIC-M) and virtual organ computer-aided analysis (VOCAL). MethodsThis study was prospective and cross-sectional. It included 45 fetuses each from mothers with pregestational DMand healthy mothers, with gestation ages ranging from 20 to 36.6 weeks. The fetal cardiac volumes were obtainedand analyzed by STIC and VOCAL methods. MAPSE and TAPSE were measured by STIC-M in the apical or basal fourchamberview. The values of the right (RV) and left ventricular (LV) CO were calculated by STIC and VOCAL. ResultsThe median values of TAPSE were 6.1 and 6.2 mm in the diabetic and control groups (P<0.001), respectively. The medianvalues of MAPSE were 4.6 mm in the fetuses of mothers with diabetes and 4.8 mm in fetuses of healthy mothers. The fetal LV CO (60.4 L/min vs. 71.1 L/min; P=0.033, respectively) and RV CO (65.2 vs. 70.1 L/min; P=0.026, respectively)were lower in the pregestational DM group than in the control group. A significant effect of pregestational DM wasobserved in all functional parameters after adjusting, with fetal heart rate as covariant. There was moderate significantpositive correlation between MAPSE and LV CO (r=0.53; P=0.0001) and between TAPSE and RV CO (r=0.46; P=0.0001). ConclusionSignificant difference in functional parameters (TAPSE, MAPSE and LV CO) obtained by STIC and VOCAL wereobserved in the fetuses of the pregestational DM group compared to those of the control group.

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