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        Immediate Effect of Needling at CV-12 (Zhongwan) Acupuncture Point on Blood Glucose Level in Patients with Type 2 Diabetes Mellitus: A Pilot Randomized Placebo-Controlled Trial

        Ranjan Kumar,A. Mooventhan,Nandi Krishnamurthy Manjunath 사단법인약침학회 2017 Journal of Acupuncture & Meridian Studies Vol.10 No.4

        Introduction: Diabetes mellitus is a major global health problem. Needling at CV-12 has reduced blood glucose level in diabetic rats. The aim of this study was to evaluate the effect of needling at CV-12 (Zhongwan) on blood glucose level in patients with type 2 diabetes mellitus (T2DM). Materials and Methods: Forty T2DM patients were recruited and randomized into either the acupuncture group or placebo control group. The participants in the acupuncture group were needled at CV-12 (4 cun above the center of the umbilicus), and those in the placebo control group were needled at a placebo point on the right side of the abdomen (1 cun beside the CV- 12). For both groups, the needle was retained for 30 minutes. Assessments were performed prior to and after the intervention. Statistical analysis was performed using SPSS version 16. Results: There was a significant reduction in random blood glucose level in the acupuncture group compared to baseline. No such significant change was observed in the placebo control group. Conclusion: The result of this study suggests that 30 minutes of needling at CV-12 might be useful in reducing blood glucose level in patients with T2DM.

      • KCI등재

        Effect of Needling at CV-12 (Zhongwan) on Blood Glucose Levels in Healthy Volunteers: A Pilot Randomized Placebo Controlled Trial

        Sriloy Mohanty,A. Mooventhan,Nandi Krishnamurthy Manjunath 사단법인약침학회 2016 Journal of Acupuncture & Meridian Studies Vol.9 No.6

        Introduction: Acupuncture, a key part of traditional Chinese medicine, is used to relieve symptoms of diabetes mellitus. The aim of this study was to evaluate the effect of needling CV-12 (Zhongwan) on blood glucose levels in healthy volunteers. Materials and methods: Thirty-six individuals were recruited and randomized into either the acupuncture group or the placebo control group. The participants in the acupuncture group were needled at CV-12 (4 cun above the center of the umbilicus), and those in the placebo control group were needled at a nonexisting “sham” point on the right side of the abdomen (1 cun beside the CV-12)da nonacupuncture point. For both groups, the needle was retained for 20 minutes without stimulation. Assessments were performed prior to and after the intervention. Statistical analysis was performed using the Statistical Package for the Social Sciences, version 16. Results: The result of this study showed a mild reduction in random blood glucose (RBG) levels in the acupuncture group and a mild increase in RBG levels in the placebo control group. However, these changes were not statistically significant both within and between groups.

      • KCI등재후보

        Regulation of autonomic functions following two high frequency yogic breathing techniques

        Joydeb Mondal,Ragavendrasamy Balakrishnan,Manjunath Nandi Krishnamurthy 셀메드 세포교정의약학회 2015 셀메드 (CellMed) Vol.5 No.1

        Yoga is an ancient Indian system of life, encompassing various practices including practices for self-discipline and also for regulating the health states of the individual, being practiced for thousands of years. The present study aims at understanding the effect of two high frequency breathing practices over autonomic nervous system. Forty healthy male volunteers of age 21 ± 2 years with 9 ± 3 months of Yoga practice experience were recruited. The two high frequency Yoga breathing practices, kapalabhati (KB) and bhastrika (BH) were given as interventions randomly on either of the two days to minimise laboratory bias. They were assessed before and immediately after the interventions for heart rate, respiratory rate, heart rate variability (HRV), blood pressure and peripheral oxygen saturation. There was a significant increase in heart rate (p < 0.01; p < 0.001), systolic blood pressure (p < 0.01; p < 0.001), NN50 (p < 0.01; p < 0.001) component of HRV for both KB and BH groups respectively. There was a significant reduction in respiratory rate in both the groups (p < 0.001, and p < 0.05, BH and KB respectively) immediately following intervention. A significant increase in LF component of HRV and reduction in Diastolic blood pressure and high frequency (HF) component following KB was also observed (p < 0.05, for all comparisons). The Mean peripheral oxygen saturation remained unaltered in both the groups (p > 0.05). The results suggest that high frequency yoga breathing practices induce physiological arousal immediately as evidenced by increased blood pressure and heart rate. The sympathetic arousal was more following KB session as evidenced by an increased diastolic blood pressure, LF power and a decrease in HF power of HRV as compared to the BH session.

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