http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Detection of Thiocholine Ions with Cobalt Phthalocyanine Mediated Screen Printed Electrode
Jie-Kai Er,윤용진,Sum Huan Ng,King Ho Holden Li,신충수,Pei-Chen Su,Nam Beng Tay,Wei Wang 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.
Acetylcholine (ACh) is a neurotransmitter that is responsible for many of our bodily functions while acetylcholineesterase (AChE) isits enzyme. Certain nerve agents inhibit AChE to cause malfunctions of our body system. To detect those agents, the concentrationof AChE by-product, choline, is used as a detection marker. Using a screen printed electrode and acetylthiocholine (ATCh) as areplacement for ACh, amperometry is employed to detect the concentration of the AChE-ATCh reaction by-product, thiocholine. Results showed that 0.1 V is the optimum potential for thiocholine detection. Voltages of 0.2 V and 0.3 V also produced similar currentmagnitudes. From 0.225 mM to 0.9 mM of thiocholine, the amperometry current exhibits a linear relation with concentration. Thesensitivity electrode is around 2.53 μA/mM. A flow rate of 100 μL/min is chosen as it is close to the saturation oxidation rate of theelectrode and is useful in practical situations. Taking into account the errors met at 0.1 V, the sensitivity of the system is calculatedto a minimum of 0.04 mM.