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Studying the Physical Parameters of a Solid State Nuclear Track Detector
Nabil M. Hassan,Abdel Fattah Hafez 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.9
Solid state nuclear track detectors (SSNTDs) are widely used to measure various types of ionizingradiation. Thus, studying the physical parameters of SSNTDs, such as the bulk etch rate, the tracketching efficiency and detector sensitivity which could affect the registration efficiency, is important. This paper presents a simple technique used to study the dependence of those characteristic physicalparameters of SSNTDs on the alpha-particle energy. The detector sensitivity and the alpha trackdiameter were found to decrease exponentially with increasing alpha-particle energy’s, which impliesthat the SSNTDs can be used as alpha-particle spectrometers. The bulk etch rates of the LR-115and the CR-39 detectors were found to be 3.75 ± 0.21 µm h−1 and 1.72 ± 0.14 µm h−1, respectively. Moreover, the calibration coefficients of the LR-115 and the CR-39 detectors, placed in a diffusioncup with a fiberglass filter exposed to radon source inside a 50 L calibration chamber (supplied byGenitron, Germany), were found to be 0.036 ± 0.004 and 0.17 ± 0.03 [-tracks cm−2 per (Bq m−3day)], respectively.
Characterization of saturation of CR-39 detector at high alpha-particle fluence
M. El Ghazaly,Nabil M. Hassan 한국원자력학회 2018 Nuclear Engineering and Technology Vol.50 No.3
The occurrence of saturation in the CR-39 detector reduces and limits its detection dynamic range;nevertheless, this range could be extended using spectroscopic techniques and by measuring the netbulk rate of the saturated CR-39 detector surface. CR-39 detectors were irradiated by 1.5 MeV high alphaparticlefluence varying from 0.06 108 to 7.36 108 alphas/cm2 from Am-241 source; thereafter, theywere etched in a 6.25N NaOH solution at a temperature of 70 C for different durations. Net bulk etch ratemeasurement of the 1.5 MeV alpha-irradiated CR-39 detector surface revealed that rate increases withincreasing etching time and reaches its maximum value at the end of the alpha-particle range. It is alsocorrelated with the alpha-particle fluence. The measurements of UVeVisible (UVeVis) absorbance at 500and 600 nm reveal that the absorbance is linearly correlated with the fluence of alpha particles at theetching times of 2 and 4 hour. For extended etching times of 6, 10, and 14.5 hour, the absorbance issaturated for fluence values of 4.05 108, 5.30 108, and 7.36 108 alphas/cm2. These new methodspave the way to extend the dynamic range of polymer-based solid state nuclear track detectors (SSNTDs)in measurement of high fluence of heavy ions as well as in radiation dosimetry.
Abouzied, Mekky Mohammed,Eltahir, Heba M.,Fawzy, Michael Atef,Abdel-Hamid, Nabil Mohie,Gerges, Amany Saber,El-Ibiari, Hesham Mohmoud,Nazmy, Maiiada Hassan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3
Purpose: To find parameters that can increase alpha-fetoprotein (AFP) sensitivity and so help in accurate diagnosis and rapid management of hepatocullular carcinoma (HCC), as AFP has limited utility of distinguishing HCC from benign hepatic disorders for its high false-positive and false negative rates. Materials and Methods: Serum levels of AFP, 5'-nucleotidase enzyme activity (5-NU) and leucine aminopeptidase enzyme (LAP) activity were measured in 40 individuals. Results: LAP and 5'NU were elevated in HCC at p<0.001. Pearson correlation coefficients showed that changes in AFP exhibited positive correlation with both 5'-NU and LAP at (p<0.001). The complementary use of LAP only with AFP resulted in an increase in sensitivity of AFP from 75% to 90% in detecting HCC. The complementary use of both LAP and 5-NU with AFP resulted in an increased sensitivity of AFP in detecting HCC from 75% to 95%. Conclusions: LAP and 5-FU can be determined in HCC patients in combination with AFP to improve its sensitivity and decrease false negative results.