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- 저자 : Musa Yigit (검색결과 1 건)
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Neutrophil to Lymphocyte Ratio in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy
Alime Gunes,Musa Yigit,Levent Tok,Ozlem Tok 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.2
Purpose: To evaluate the neutrophil to lymphocyte ratio (NLR) in patients with nonarteritic anterior ischemic opticneuropathy (NAION). Methods: We investigated 112 subjects comprising 56 patients with NAION and 56 healthy controls at SüleymanDemirel University. Complete blood count, demographic, and clinic data from NAION patients were evaluatedin this study. The NLR was calculated in all individuals and compared between the patient and controlgroups. Cut-off values were also determined. Then, the relationship between NLR and visual outcomes wasinvestigated. Results: The cut-off value for NLR was 1.64. NLR values were significantly higher in NAION patients than inhealthy subjects (p < 0.001) and were directly correlated with erythrocyte sedimentation rate levels (r = 0.263,p = 0.006). Also, the NLR value was associated with visual outcomes. Receiver operator characteristic curveanalysis revealed a 0.63 area under the curve (confidence interval, 53.7% to 74.1%), 85% sensitivity and 41%specificity at the cut-off NLR value. Conclusions: The NLR may be a biomarker with good sensitivity that is quick, cost effective and easily detectedin serum. It can be used in clinical practice to predict a NAION patient’s prognosis in terms of visual outcomes.
KCI
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