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- 저자 : Muhammad Fahad Ehsan (검색결과 2 건)
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Biocompatibility of cobalt iron oxide magnetic nanoparticles in male rabbits
Furhan Iqbal,Tanveer Ahmad Tabish,Muhammad Naeem Ashiq,Muhammad Azeem Ullah,Shahid Iqbal,Muhammad Latif,Muhammad Ali,Muhammad Fahad Ehsan 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.7
Present study was conducted to study the in vivo biocompatibility of cobalt iron oxide magnetic nano-particles (CoFe2O4 MNPs) in rabbits. CoFe2O4 MNPs were synthesized by the conventional micro emulsion technique in crystallite size range of 30 to 50 nm. The lattice constant (a) and cell volume were found to be 8.386 Å and 589.75 Å3, respectively, revealed by XRD. Subject animals were divided in three groups--low dose, high dose and control group without nanoparticles implantation for biocompatibility evaluation. CoFe2O4 was intraperitoneally implanted in rabbits: low dose (1mg CoFe2O4/Kg body weight) and high dose (10mg CoFe2O4/Kg body weight). Blood, serum and histological study of vital organs (liver, heart, kidney and spleen) were carried out in seven days of time protocol after sacrificing of animals. Results indicated that CoFe2O4 had drastically affected the blood chemistry in a dose-dependent manner as RDWa (P=0.01), Platelet (P<0.001) and Plateletcrit (P<0.001) concentrations reduced significantly in low dose and high dose CoFe2O4 treatments as compared to sham treated control group. Histological analysis revealed that CoFe2O4 exposure resulted in disordered and abnormal histology of liver, kidney and that of muscles at surgical site. It is concluded that CoFe2O4 has low biocompatibility and higher toxicity levels in living system at the applied doses.
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Junaid Ali,Abdullah Muhammad,Bano Nigarish,Noreen Faiqa,Shah Syed Imran Abbas,Alshgari Razan A.,Mohammad Saikh,Manzoor Sumaira,Ehsan Muhammad Fahad,Ashiq Muhammad Naeem 한국세라믹학회 2024 한국세라믹학회지 Vol.61 No.3
To drive clean and sustainable fuel production via water electrolysis, development of high-performing, cost-eff ective elec- trocatalysts rich in earth elements without relying on precious metals or costly materials is crucial. In this study, strontium selenide (SrSe), copper sulfi de (CuS), and composite SrSe@CuS via a traditional coprecipitate method under alkaline con- ditions are synthesized. Characterization techniques including X-ray diff raction, Transmission electron microscopy, Field emission scanning electron microscopy, and Brunauer–Emmett–Teller surface area analysis are employed to analyze the structure, morphology, and surface characteristics. The larger surface area of 123 m 2 g−1 and lower crystalline size (46.43 nm) of SrSe@CuS nanosheets show more active sites for oxygen evolution reaction. The oxygen evolution activity displayed overpotentials of 290 mV, a lower tafel slope of 67 mV dec −1, and Lower charge transfer resistance (RCT) values of SrSe@ CuS nanosheets (1.82 Ω) surpassing the individual SrSe and CuS nanosheets. Notably, the SrSe@CuS nanosheets exhibited remarkable stability, maintaining an oxygen evolution reaction (OER) activity of 10 mA cm −2 for over 50 h and sustaining a negligible loss in performance even after 50,000 cycles of repetitive cyclivoltammetry scans. These fi ndings highlight their potential applicability in energy conversion and storage systems.
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