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Antioxidant Properties of Methanolic Extracts from Leaves of Rhazya stricta
Shahid Iqbal,M.I. Bhanger,Mubeena Akhtar,Farooq Anwar,Khawaja Raees Ahmed,Tabraz Anwer 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.2
Because of increased safety concerns about synthetic antioxidants, exploitation of cheaper and safer sourcesof antioxidants based on natural origin is the focus of research nowadays. Rhazya stricta is a medicinally important plant na-tive to South Asia. Extraction of antioxidants was carried out in different solvent systems, i.e., water, 80% methanol, 70%ethanol, and diethyl ether. The methanolic extract exhibited the highest total phenolic content among the extracts; thereforefor further studies the methanolic extract was employed. Antioxidant activity measurement in the linoleic acid system, metalchelating activity, reducing power, scavenging effect on 1,1-diphenyl-2-picrylhydrazyl free radical, and superoxide anion rad-ical scavenging activity were taken as the parameters for assessment of antioxidant potential of methanolic extracts. Resultswere compared with .-tocopherol and the synthetic antioxidant butylated hydroxyanisole. The antioxidant potential of methano-lic extracts of R. strictaleaves was comparable with previously exploited potent antioxidants and is strongly concentrationdependent.