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      • SCOPUSKCI등재

        Case Reports : Intravitreal Bevacizumab for Treatment of Refractory Central Serous Choroidoretinopathy

        ( Morteza Entezari ),( Alireza Ramezani ),( Mehdi Yaseri ) 대한안과학회 2012 Korean Journal of Ophthalmology Vol.26 No.2

        In a clinical case series, 5 patients with not-resolved central serous choroidoretinopathy (CSC) lasting more than 1 year received one intravitreal bevacizumab injection (IVB, 1.25 mg) injection. All patients underwent a through ophthalmic examination 1 day, 1 week, and 1, 2, and 6 months after the injection. Best corrected visual acuity (BCVA) and central macular thickness were compared before and after treatment by optical coherence tomography. Mean BCVA was improved significantly (p=0.020) from 0.60±0.25 to 0.50±0.18 and 0.29±0.19 logarithm of minimum angle of resolution at 6 and 18 weeks, respectively. Central macular thickness was also decreased significantly (p=0.010) from 370±65 to 208±23 μm at 4 months. No recurrence was occurred during follow-up. IVB injection may have beneficial effect in the treatment of refractory CSC.

      • KCI등재

        Analgesic Effect of Topical Sodium Diclofenac before Retinal Photocoagulation for Diabetic Retinopathy: A Randomized Doublemasked Placebo-controlled Intraindividual Crossover Clinical Trial

        Alireza Ramezani,Morteza Entezari,Mohammad Mehdi Shahbazi,Yosef Semnani,Homayoun Nikkhah,Mehdi Yaseri 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.2

        Purpose: To evaluate the analgesic effect of topical sodium diclofenac 0.1% before retinal laser photocoagulationfor diabetic retinopathy. Methods: Diabetic patients who were candidates for peripheral laser photocoagulation were included in a randomized,placebo-controlled, intraindividual, two-period, and crossover clinical trial. At the first session andbased on randomization, one eye received topical sodium diclofenac 0.1% and the other eye received an artificialtear drop (as placebo) three times before laser treatment. At the second session, eyes were given thealternate drug. Patients scored their pain using visual analogue scale (max, 10 cm) at both sessions. Patientsand the surgeon were blinded to the drops given. Difference of pain level was the main outcome measure. Results: A total of 200 eyes of 100 patients were enrolled. Both treatments were matched regarding the appliedlaser. Pain sensation based on visual analogue scale was 5.6 ± 3.0 in the treated group and 5.5 ± 3.0 in thecontrol group. The calculated treatment effect was 0.15 (95% confidence interval, –0.27 to 0.58; p = 0.486). The estimated period effect was 0.24 (p = 0.530) and the carryover effect was not significant (p = 0.283). Conclusions: Pretreatment with topical sodium diclofenac 0.1% does not have any analgesic effect during peripheralretinal laser photocoagulation in diabetic patients.

      • KCI등재

        Predictors and Outcomes of Vitrectomy and Silicone Oil Injection in Advanced Diabetic Retinopathy

        Alireza Ramezani,Hamid Ahmadieh,Amin Rozegar,Masoud Soheilian,Morteza Entezari,Siamak Moradian,Mohammad H Dehghan,Homayoun Nikkhah,Mehdi Yaseri 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.3

        Purpose: To evaluate visual and anatomical results and identify factors that influence vitrectomy and silicone oil(SO) injection outcomes in proliferative diabetic retinopathy (PDR). Methods: This retrospective study included 236 eyes with PDR that were undergoing vitrectomy and SO injectionwith >3-month follow-up. The primary outcomes were final best-corrected visual acuity (BCVA) and retinalattachment rate. Results: At the final visit (mean, 88 ± 58 weeks), complete, partial, and no retinal attachment were observed in86.9%, 10.6%, and 2.5% of patients, respectively. A total of 155 eyes had experienced SO removal, while 81had SO in place. The mean initial BCVA was 1.9 ± 0.7 logarithm of the minimum angle of resolution (logMAR)and significantly improved to 1.7 ± 0.8 logMAR (p = 0.001). Initial macular detachment (adjusted odds ratio[AOR], 0.25), development of iatrogenic break (AOR, 0.25), and use of heavy SO (AOR, 0.13) were independentlyassociated with a lower risk of final retinal attachment, and SO removal was associated with a higherincidence (AOR, 7.55). Better baseline BCVA was associated with a higher risk of final BCVA ≥20 / 200. Conclusions: Despite an encouraging outcome based on anatomical data in advanced PDR treated with vitrectomyand SO, the functional prognosis was not satisfying for patients. Eyes with better vision at baseline hada more favorable prognosis, whereas eyes with initial macular detachment, intraoperative iatrogenic break, orheavy SO showed more unfavorable outcomes. In selected cases, extending the time of SO use did not worsenthe prognosis.

      • KCI등재

        풍차날개의 공력 성능 향상과 유동 박리 감소를 위한 수동 유동 제어에 대한 DES 해석

        Mohammad Moshfeghi,Shahrokh Shams,Morteza Ramezani,허남건 한국전산유체공학회 2018 한국전산유체공학회지 Vol.23 No.4

        Power generation of a horizontal axis wind turbine is severely dependent upon aerodynamic phenomena over the blade, especially the flow separation. Since, usually the local AoA (Angle of Attack) in the inner and middle parts of a blade is much greater than the separation onset, the blade section encounters a highly separated flow or even stall condition. Hence, flow control methods can be employed in order to reduce or weaken the negative effects of the separation. This paper investigates the effects of a recently verified passive flow control method for HAWTs via a validated three dimensional DES(Detached Eddy Simulation) of split versions of the S809 airfoil. In this research, two different airfoil families with four various split width values of 0.5, 1, 2 and 4 percent of chord length are simulated at a range of angle of attack from 0 to 25 degrees. As a result of existence of the split, flow from the high-pressure zone at the lower surfaces gets injected into the separated area over the suction surfaces. The positive or negative effect of this method is mainly dependent upon split end location on the suction surface. Direction of the jet flow with respect to the free stream and also the width of split are the other important parameters. Also, the findings reveal that in each family there exists one optimal split width for which the airfoil aerodynamic performance is enhanced remarkably.

      • KCI등재

        CFD ANALYSIS OF A NEW ACTIVE FLOW CONTROL METHOD FOR WIND TURBINE AIRFOILS USING A PADDLE WHEEL INSIDE THE SPLIT OF AIRFOIL

        Mohammad Moshfeghi,Amir Maleki,Morteza Ramezani,Nahmkeon Hur(허남건) 한국전산유체공학회 2021 한국전산유체공학회지 Vol.26 No.2

        In the following years, the wind energy industry will maintain its surge during the last few decades. Meanwhile, horizontal axis wind turbines (HAWT) are the most prominent one among other wind turbines. Accordingly, enhancing blade aerodynamic performance should be the main part of study over this type of turbines. For this purpose, various active and passive flow control methods are being extensively investigated. Investigating new hybrid method is the main aim of this paper. Therefore, in this present study a novel idea, that uses a paddle wheel which is located inside the split, is investigated. This new configuration is based on the split method and the rotation of a paddle wheel that provides pulsatile flow inside the split. The flow then gets injected into the bulk flow over the airfoil, causing hybrid flow control effects. Optimized split geometry of S809 airfoil has been selected and then a paddle wheel is placed inside the split. First, the effect of split width on passing flow and separation zone was investigated. Second, the effect of rotational speed of the paddle is discussed. To this end, 2D CFD simulations using SST-k-ω turbulence model have been performed. The simulations have been conducted for a wide range of angles of attack (AOA). The results are discussed in the form of aerodynamics force coefficients as well as streamlines to compare the size of the separation area at higher angles of attack.

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