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      저자 : Mirzaamiri, Rouhollah (검색결과 1 건)
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      • Ion-beam irradiation of DLC-based nanocomposite: Creation of a highly biocompatible surface

        Penkov, Oleksiy V.,Kheradmandfard, Mehdi,Khadem, Mahdi,Kharaziha, Mahshid,Mirzaamiri, Rouhollah,Seo, Kuk-Jin,Kim, Dae-Eun Elsevier 2019 APPLIED SURFACE SCIENCE - Vol.469 No.-

        <P><B>Abstract</B></P> <P>Ion-beam irradiation of diamond-like carbon (DLC) by He ions was studied. Molecular dynamics simulation was performed to understand the effects of irradiation on the nano-topography and chemical state of the coatings and determine the optimal irradiation conditions. Then, the experiment was conducted to validate the results of the simulation and correlate surface modifications to biomedical properties. It was demonstrated that the irradiation led to the formation of a low-density and low-sp<SUP>3</SUP> content surface layer. The structural and chemical properties of the final surface were nearly independent of the initial sp<SUP>3</SUP> content and irradiation energy. The biocompatibility of DLC-based nanocomposite coatings was significantly improved by ion-beam irradiation. Nanocomposite coatings were irradiated by 1 keV He ions. Irradiation with a dose of 4.2 × 10<SUP>15</SUP> ion/cm<SUP>2</SUP> increased the adhesion of MG63 cells dramatically from 10 to ∼100%.</P> <P><B>Highlights</B></P> <P> <UL> <LI> MD models of DLC with various sp<SUP>3</SUP> content were developed. </LI> <LI> MD simulation of ion-beam irradiation of DLC was performed. </LI> <LI> DCL-based nanocomposites were irradiated by He ion beam. </LI> <LI> Effect of the ion-beam irradiation n cell adhesion was assessed. </LI> <LI> Correlations between MD simulation and experiment were established. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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