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        Smartphone App in Stroke Management: A Narrative Updated Review

        Adriano Bonura,Francesco Motolese,Fioravante Capone,Gianmarco Iaccarino,Michele Alessiani,Mario Ferrante,Rosalinda Calandrelli,Vincenzo Di Lazzaro,Fabio Pilato 대한뇌졸중학회 2022 Journal of stroke Vol.24 No.3

        The spread of smartphones and mobile-Health (m-health) has progressively changed clinical practice, implementing access to medical knowledge and communication between doctors and patients. Dedicated software called Applications (or Apps), assists the practitioners in the various phases of clinical practice, from diagnosis to follow-up and therapy management. The impact of this technology is even more important in diseases such as stroke, which are characterized by a complex management that includes several moments: primary prevention, acute phase management, rehabilitation, and secondary prevention. This review aims to evaluate and summarize the available literature on Apps for the clinical management of stroke. We described their potential and weaknesses, discussing potential room for improvement. Medline databases were interrogated for studies concerning guideline-based decision support Apps for stroke management and other medical scenarios from 2007 (introduction of the first iPhone) until January 2022. We found 551 studies. Forty-three papers were included because they fitted the scope of the review. Based on their purpose, Apps were classified into three groups: primary prevention Apps, acute stroke management Apps, and post-acute stroke Apps. We described the aim of each App and, when available, the results of clinical studies. For acute stroke, several Apps have been designed with the primary purpose of helping communication and sharing of patients’ clinical data among healthcare providers. However, interactive systems Apps aiming to assist clinicians are still lacking, and this field should be developed because it may improve stroke patients’ management.

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        Deep learning approach for the segmentation of aneurysmal ascending aorta

        Albert Comelli,Navdeep Dahiya,Alessandro Stefano,Viviana Benfante,Giovanni Gentile,Valentina Agnese,Giuseppe M. Raffa,Michele Pilato,Anthony Yezzi,Giovanni Petrucci,Salvatore Pasta 대한의용생체공학회 2021 Biomedical Engineering Letters (BMEL) Vol.11 No.1

        Diagnosis of ascending thoracic aortic aneurysm (ATAA) is based on the measurement of the maximum aortic diameter,but size is not a good predictor of the risk of adverse events. There is growing interest in the development of novel imagederivedrisk strategies to improve patient risk management towards a highly individualized level. In this study, the feasibilityand efficacy of deep learning for the automatic segmentation of ATAAs was investigated using UNet, ENet, and ERFNettechniques. Specifically, CT angiography done on 72 patients with ATAAs and different valve morphology (i.e., tricuspidaortic valve, TAV, and bicuspid aortic valve, BAV) were semi-automatically segmented with Mimics software (MaterializeNV, Leuven, Belgium), and then used for training of the tested deep learning models. The segmentation performance interms of accuracy and time inference were compared using several parameters. All deep learning models reported a dicescore higher than 88%, suggesting a good agreement between predicted and manual ATAA segmentation. We found that theENet and UNet are more accurate than ERFNet, with the ENet much faster than UNet. This study demonstrated that deeplearning models can rapidly segment and quantify the 3D geometry of ATAAs with high accuracy, thereby facilitating theexpansion into clinical workflow of personalized approach to the management of patients with ATAAs.

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