http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Mehdi Karbasian (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Designing Reliability Improvement Model Using Design Structure Matrix
Karbasian, Mehdi,Kazemi, Sayed Mohammad,Khayambashi, Bijan,Nilipour, Sayed Akbar Korean Institute of Industrial Engineers 2017 Industrial Engineeering & Management Systems Vol.16 No.4
As an inherent characteristic of any product or system, reliability is one of the parameters of design, construction and operation to be considered and controlled as an important criterion during relevant processes. The need to ensure the continuous and proper functioning of a product has led designers to pay special attention to increasing reliability. Therefore by coordinating all design experts and support groups throughout the implementation of product life cycle, the product development life cycle period can be reduced and value-creation of products increased. As a result, the existence of a comprehensive model is of vital importance. In this study, all industrial engineering techniques effective in improving reliability are first identified and then prioritized in all phases of the product life cycle using multi-criteria decision making method. Finally, using design structure matrix, priority and posteriority of all techniques is determined in each phase and a systematic model is provided to improve equipment reliability.
-
Designing Reliability Improvement Model Using Design Structure Matrix
Mehdi Karbasian,Sayed Mohammad Kazemi,Bijan Khayambashi,Sayed Akbar Nilipour 대한산업공학회 2017 Industrial Engineeering & Management Systems Vol.16 No.4
As an inherent characteristic of any product or system, reliability is one of the parameters of design, construction and operation to be considered and controlled as an important criterion during relevant processes. The need to ensure the continuous and proper functioning of a product has led designers to pay special attention to increasing reliability. Therefore by coordinating all design experts and support groups throughout the implementation of product life cycle, the product development life cycle period can be reduced and value-creation of products increased. As a result, the existence of a comprehensive model is of vital importance. In this study, all industrial engineering techniques effective in improving reliability are first identified and then prioritized in all phases of the product life cycle using multicriteria decision making method. Finally, using design structure matrix, priority and posteriority of all techniques is determined in each phase and a systematic model is provided to improve equipment reliability.
-
Seyed Davar Siadat,Farzam Vaziri,Mamak Eftekhary,Maryam Karbasian,Arfa Moshiri,Mohammad R. Aghasadeghi,Mehdi S. Ardestani,Meghdad Abdollahpour Alitappeh,Amin Arsang,Abolfazl Fateh,Shahin Najar Peeraye 질병관리본부 2015 Osong Public Health and Research Persptectives Vol.6 No.1
Objectives: Development of an efficacious vaccine against brucellosis has been a challenge for scientists for many years. At present, there is no licensed vaccine against human brucellosis. To overcome this problem, currently, antigenic determinants of Brucella cell wall such as Lipopolysaccharide (LPS) are considered as potential candidates to develop subunit vaccines. Methods: In this study, Brucella abortus LPS was used for conjugation to Neisseria meningitidis serogroup B outer membrane vesicle (OMV) as carrier protein using carbodiimide and adipic acid-mediated coupling and linking, respectively. Groups of eight BALB/c mice were injected subcutaneously with 10 ㎍LPS alone, combined LPS + OMV and conjugated LPS-OMV on 0 days, 14 days, 28 days and 42 days. Anti-LPS IgG was measured in serum. Results: The yield of LPS to OMV in LPS-OMV conjugate was 46.55%, on the basis of carbohydrate content. The ratio for LPS to OMV was 4.07. The LPS-OMV conjugate was the most immunogenic compound that stimulated following the first injection with increased IgG titer of ~ 5-fold and ~1.3-fold higher than that produced against LPS and LPS in noncovalent complex to OMV (LPS + OMV), respectively. The highest anti-LPS IgG titer was detected 2 weeks after the third injection (Day 42) of LPS-OMV conjugate. The conjugated compound elicited higher titers of IgG than LPS + OMV, that showed a 100-120-fold rise of anti-LPS IgG in mice. Conclusion: These results indicate that our conjugated LPS-OMV can be used as a brucellosis vaccine, but further investigation is required.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
