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- 저자 : Maryam Salahi (검색결과 2 건)
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Maryam Meshksar,Fatemeh Salahi,Fatemeh Zarei-Jelyani,Mohammad Reza Rahimpour,Mohammad Farsi 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.111 No.-
This research focuses on controlling the morphology and crystalline phase of hollow Al2O3 spheres as asupporting material of Ni-based catalysts for the first time, which is then applied as a catalyst of hightemperaturesteam methane reforming (SMR) process. For this purpose, the effects of hydrothermal time,the concentration of alumina salt, and calcination temperature on the structure of support are investigatedand adjusted and then loaded with 15–25 wt.% Ni contents. The morphology of synthesized hollowalumina samples and 20Ni/H-Al2O3 catalyst before and after reaction are characterized using XRD,FESEM, TEM, H2-TPR, CO2-TPD, EDX, FTIR, N2 adsorption/desorption, and mapping techniques. Thehydrothermal time of 72 h, calcination temperature of 800 C, and alumina salt concentration of1.00 M resulted in the spherical morphology of hollow Al2O3 with 236.26 m2/gr surface area and highcrystallinity. Among different Ni loadings, 20Ni/H-Al2O3 had the highest CH4 conversion of 87.75% andH2 yield of 92.09% at 700 C. This catalyst also depicted stable performance during 12 h SMR reactionat 700 C with low carbon deposited contents.
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Abolfazl Razzaghdoust,Mahdi Ghajari,Abbas Basiri,Peyman Mohammadi Torbati,Anya Jafari,Mohammad-Reza Fattahi,Maryam Salahi,Bahram Mofid 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.3
Purpose: A readily accessible biomarker to identify which patients with bladder cancer are more likely to respond to neoadjuvant chemotherapy (NAC) could help clinicians avoid unnecessary chemotherapy and prevent its subsequent complications in some patients. The primary objective of this study was to investigate the association of immunohistochemical markers of tumor subtype with response to NAC and survival of patients with muscle-invasive bladder cancer (MIBC). Materials and Methods: MIBC patients treated with NAC were retrospectively included. The tissue microarrays were assembled from transurethral resection of bladder tumor (TURBT) specimens and immunohistochemistry (IHC) was performed. The association of independent variables, including IHC markers, and clinical covariates with clinical complete response to NAC and with overall survival was assessed by using logistic regression and Cox proportional hazard regression analysis, respectively. Kaplan-Meier curves were plotted for different IHC-based tumor subtypes. Results: Data from 140 MIBC patients treated with NAC were retrospectively reviewed. A total of 63 patients with available TURBT specimens were eligible to be included in the analysis. Our results showed that the IHC signature of KRT5/6(+)/KRT20(−), as a combined marker of basal subtype, was the only covariate significantly associated with complete response to NAC (p=0.037). Moreover, we found no statistically significant differences in overall survival between different IHC-based subtypes (p=0.721). Conclusions: The IHC expression of KRT5/6 and KRT20, as a readily accessible combined marker, may help us to identify the patients most likely to benefit from chemotherapy. The clinical utility of this marker needs to be established in larger prospective studies.
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