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      • Terahertz radiation from plasma filament generated by two-color laser gas-plasma interaction

        Magesh Kumar, K. K.,Kumar, M.,Yuan, T.,Sheng, Z. M.,Chen, M. Cambridge University Press 2015 Laser and particle beams Vol.33 No.3

        <B>Abstract</B><P>We develop a theoretical model for terahertz (THz) radiation generation, when an intense short laser pulse (ω1, <I>k</I>1) is mixed with its frequency shifted second harmonic (ω2, <I>k</I>2), where ω2 = 2ω1 + ωT and ωT is in the THz range in the plasma. The lasers exert a ponderomotive force on the electrons and drive density perturbations at (2ω1, 2<I>k</I>1) and (ω2 − ω1, <I>k</I>2 − <I>k</I>1). These density perturbations couple with the oscillatory velocities of the electron due to the lasers and produce a nonlinear current at (ω2 − 2ω1, <I>k</I>2 − 2<I>k</I>1). This current acts as an antenna to produce the THz radiation. The THz power depends upon the square of plasma density and $I_1^2 {I_2}$, where <I>I</I>1 and <I>I</I>2 are the intensities of fundamental and second harmonic laser. The radiation is mainly along the forward direction. Two-dimensional particle-in-cell simulations are used to study the near-field radiation properties.</P>

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        Antimicrobial Efficacy of Allium cepa and Zingiber officinale Against the Milk-Borne Pathogen Listeria monocytogenes

        Arasu Abirami,Prabha Nagaram,Devi Durga,Issac Praveen Kumar,Alarjani Khaloud Mohammed,Al Farraj Dunia A.,Aljeidi Reem A.,Tayyeb Jehad Zuhair,Guru Ajay,Arockiaraj Jesu,Mohan Magesh,Hussein Dina S. 한국미생물학회 2023 The journal of microbiology Vol.61 No.11

        Listeria monocytogenes is an important food-borne pathogen that causes listeriosis and has a high case fatality rate despite its low incidence. Medicinal plants and their secondary metabolites have been identified as potential antibacterial substances, serving as replacements for synthetic chemical compounds. The present studies emphasize two significant medicinal plants, Allium cepa and Zingiber officinale, and their efficacy against L. monocytogenes. Firstly, a bacterial isolate was obtained from milk and identified through morphology and biochemical reactions. The species of the isolate were further confirmed through 16S rRNA analysis. Furthermore, polar solvents such as methanol and ethanol were used for the extraction of secondary metabolites from A. cepa and Z. officinale. Crude phytochemical components were identified using phytochemical tests, FTIR, and GC–MS. Moreover, the antibacterial activity of the crude extract and its various concentrations were tested against L. monocytogenes. Among all, A. cepa in methanolic extracts showed significant inhibitory activity. Since, the A. cepa for methanolic crude extract was used to perform autography to assess its bactericidal activity. Subsequently, molecular docking was performed to determine the specific compound inhibition. The docking results revealed that four compounds displayed strong binding affinity with the virulence factor Listeriolysin-O of L. monocytogenes. Based on the above results, it can be concluded that the medicinal plant A. cepa has potential antibacterial effects against L. monocytogenes, particularly targeting its virulence.

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