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RISS 인기검색어
- 검색키워드
- 저자 : Madanat, Samer Michel (검색결과 5 건)
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Optimal levee installation planning for highway infrastructure protection against sea level rise
Papakonstantinou, Ilia,Lee, Jinwoo,Madanat, Samer Michel Elsevier 2019 TRANSPORTATION RESEARCH PART D-TRANSPORT AND ENVIR Vol.77 No.-
<P><B>Abstract</B></P> <P>Sea level rise predictions have motivated research towards the protection of shoreline infrastructures, including transportation systems. Transportation network interactions in cases of inundation can lead to severe disruptions that cause capacity and accessibility reduction and thus considerable delays, especially due to congestion feedback, because congestion occurring due to an inundated link or a link that becomes isolated through inundation of one of its nodes can lead to delays in other parts of the network, due to queue spillback or traffic rerouting. This paper describes a decision tool to support infrastructure protection planning against sea level rise. A simulation-based optimization model is designed to minimize delays occurring in a transportation system under inundation. The model considers budget constraints, hydrodynamic interactions within the shoreline, as well as traffic assignment in the network. The case study focuses on San Francisco Bay area, for a 0.5 m sea level rise that is expected in 2054 and may increase highway users’ travel time by 37%. The results show that the optimal strategies vary according to the available budget, and that there exist relatively critical shorelines to protect in order to reduce the traffic disruptions. We anticipate our research to provide a general framework for transportation infrastructure protection planning against sea level rises.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A simulation based bi-level model minimizes network delays due to inundations. </LI> <LI> Budget constraints, hydrodynamic and traffic interactions are considered. </LI> <LI> Findings are applied to a real world network in California for 0.5 m sea level rise. </LI> <LI> The optimal strategies vary according to the available budget. </LI> <LI> There exist critical shorelines to protect, to reduce the traffic disruptions. </LI> </UL> </P>
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Prognostic effect of blood transfusion in children with acute lymphoblastic leukemia
Khaldoun Alkayed,Ammar Al Hmood,Faris Madanat 대한혈액학회 2013 Blood Research Vol.48 No.2
Background Most children with acute lymphoblastic leukemia (ALL) receive blood transfusions. Transfusions may affect ALL outcomes through transfusion-related immunomodulation (TRIM). Methods We analyzed overall survival (OS) and event-free survival (EFS) in relation to leukocyte reduced and irradiated (LR/IRR) blood products transfused during the induction phase in 136 children with ALL. Hazard ratios (HRs) for death and relapse were estimated through Cox regression analysis. Results One hundred and twenty patients (89%) were transfused with packed red blood cells (PRBCs) and 79 (58%) with single donor platelets (SDPs). The median number of transfusions was 2 (interquartile range [IQR]=1‒3 events) and 1 (IQR=0‒3 events) for PRBCs and SDPs, respectively. Patients who had white blood cell (WBC) count >50,000×109/L, were classified as high risk according to the high National Cancer Institute criteria, displayed a T cell phenotype, or were minimal residual disease-positive at end of induction were more likely to receive >3 transfusions during induction (P=0.001, 0.002, 0.03, and 0.01, respectively). In univariate analysis, PRBC, SDP, and fresh frozen plasma transfusions did not have any significant association with relapse or death. For PRBC transfusions, the HRs for EFS and OS were 1.02 (95% CI, 0.85‒1.24; P=0. 76) and 1.03 (95% CI, 0.83‒1.27; P=0.76), respectively. For SDP transfusions, HRs were 1.03 (95% CI, 0.90‒1.18; P=0.64) and 0.98 (95% CI, 0.80‒1.20; P=0.87) for EFS and OS, respectively. Conclusion LR/IRR blood products may not confer a TRIM effect in childhood ALL and are unlikely to affect outcome.
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Prognostic effect of blood transfusion in children with acute lymphoblastic leukemia
Khaldoun Alkayed,Ammar Al Hmood,Faris Madanat 대한혈액학회 2013 Blood Research Vol.48 No.2
Background Most children with acute lymphoblastic leukemia (ALL) receive blood transfusions. Transfusions may affect ALL outcomes through transfusion-related immunomodulation (TRIM). Methods We analyzed overall survival (OS) and event-free survival (EFS) in relation to leukocyte reduced and irradiated (LR/IRR) blood products transfused during the induction phase in 136 children with ALL. Hazard ratios (HRs) for death and relapse were estimated through Cox regression analysis. Results One hundred and twenty patients (89%) were transfused with packed red blood cells (PRBCs) and 79 (58%) with single donor platelets (SDPs). The median number of transfusions was 2 (interquartile range [IQR]=1‒3 events) and 1 (IQR=0‒3 events) for PRBCs and SDPs, respectively. Patients who had white blood cell (WBC) count >50,000×109/L, were classified as high risk according to the high National Cancer Institute criteria, displayed a T cell phenotype, or were minimal residual disease-positive at end of induction were more likely to receive >3 transfusions during induction (P=0.001, 0.002, 0.03, and 0.01, respectively). In univariate analysis, PRBC, SDP, and fresh frozen plasma transfusions did not have any significant association with relapse or death. For PRBC transfusions, the HRs for EFS and OS were 1.02 (95% CI, 0.85‒1.24; P=0. 76) and 1.03 (95% CI, 0.83‒1.27; P=0.76), respectively. For SDP transfusions, HRs were 1.03 (95% CI, 0.90‒1.18; P=0.64) and 0.98 (95% CI, 0.80‒1.20; P=0.87) for EFS and OS, respectively. Conclusion LR/IRR blood products may not confer a TRIM effect in childhood ALL and are unlikely to affect outcome.
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The Effects of Dielectric Coatings on Electron Emission from Tungsten
Al-Qudah, Ala'a M.,Alnawasreh, Shady S.,Madanat, Mazen A.,Trzaska, Oliwia,Matykiewicz, Danuta,Alrawshdeh, Saad S.,Hagmann, Mark J.,Mousa, Marwan S. Korean Society of Microscopy 2017 Applied microscopy Vol.47 No.1
Field electron emission measurements were performed on dielectric-coated tungsten emitters, with apex radii in the nanometer and micrometer range, which were prepared by electrochemical etching in NaOH solution. Measurements were performed in a field electron microscopy (FEM) with a base pressure <$10^{-6}$ Pascal ($10^{-8}$ mbar). Four different types of dielectric were used, namely: (1) Clark Electromedical Instruments epoxylite resin, (2) Epidian 6 produced by Ciech Sarzyna S. A., (3) a Radionox solution of colloidal graphite; and (4) Molyslip 2001 E compound ($MoS_2$ and MoS). Current-voltage measurements and FEM images were used to investigate the characteristics of these composite emitters, and to assess how the different types of dielectric coating affect the suitability of the composite emitter as a potential electron source.
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Epoxylite Influence on Field Electron Emission Properties of Tungsten and Carbon Fiber Tips
Alnawasreh, Shady S,Al-Qudah, Ala'a M,Madanat, Mazen A,Bani Ali, Emad S,Almasri, Ayman M,Mousa, Marwan S Korean Society of Microscopy 2016 Applied microscopy Vol.46 No.4
This investigation deals with the process of field electron emission from composite microemitters. Tested emitters consisted of a tungsten or carbon-fiber core, coated with a dielectric material. Two coating materials were used: (1) Clark Electromedical Instruments Epoxylite resin and (2) Epidian 6 Epoxy resin (based on bisphenol A). Various properties of these emitters were measured, including the current-voltage characteristics, which are presented as Fowler-Nordheim plots, and the corresponding electron emission images. A field electron microscope with a tip (cathode) to screen (anode) distance of 10 mm was used to electrically characterize the emitters. Measurements were carried out under ultra-high vacuum conditions with a base pressure of $10^{-6}$ Pascal ($10^{-8}$ mbar).
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