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Du Jingjing,Ma Yuedong,Wang Yanyun 한국탄소학회 2024 Carbon Letters Vol.34 No.1
This paper presents an electrochemical immunosensor using a graphene/multi-walled carbon nanotube (MWCNT) composite platform for detecting the cardiovascular marker C-reactive protein (CRP). The immunosensor exhibited a linear detection range of 0.20–100 ng/mL CRP with a low limit of detection reaching 0.081 ng/mL. The composite material provided a 3D porous structure that allowed efficient antibody immobilization and minimized steric hindrance. The sensor showed high specificity, with minimal response to interfering substances. Using differential pulse voltammetry, the immunosensor demonstrated exceptional precision, rapid detection, and a direct correlation between CRP concentration and sensor response current. Overall, this work highlights the potential of the graphene/MWCNT composite platform as a robust tool for early CRP detection and cardiovascular disease risk assessment. The immunosensor provides sensitive and selective CRP quantification that could enable timely clinical intervention for at-risk individuals.
Guoqiang Yang,Shali Xiao,Yuedong Ma,Liuqiang Zhang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.4
A capacitive Frisch-grid CdZnTe detector with different lengths of the Frisch rings has beenfabricated, and the influence of infrared (IR) stimulation on the spectral performance of the detectorhas been investigated. IR stimulation at a wavelength (940 nm), close to the absorption edge ofthe CdZnTe, was found to improve the detector’s spectral performance significantly. IR radiationwas noted to influence the detector’s sensitivity, changing the equilibrium between free and trappedcarriers and improving the charge collection. The degree of improvement was different for detectorswith different lengths of the Frisch rings and depended on the weighting potential distribution andthe IR illumination intensity. For example, improvement was obtained in the energy resolution(FWHM) at 662 keV from 3.3% without illumination to 2.3% with a low intensity (120 μW) of IRillumination for the capacitive Frisch-grid CdZnTe detector with an 8-mm-long Frisch ring. Goodenergy resolution could be obtained even at low operating voltages.