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Phytochemical and Pharmacological Investigations on Moringa peregrina (Forssk) Fiori
Seham A. Elbatran,Omar M. Abdel-Salam,Khaled A. Abdelshfeek,Naglaa M. Nazif,Shams I. Ismail,Faiza M. Hammouda 한국생약학회 2005 Natural Product Sciences Vol.11 No.4
Investigation of M. peregrina aerial parts revealed the isolation and identification of 4-flavonoidalcompounds, quercetin, quercetin-3-0-rutinoside (rutin), chrysoeriol-7-0-rhamnoside and 6,8,3/,5/-tetramethoxyapigenin. The compounds were identified by TLC, PC, MS, and H1-NMR. The fatty acids and unsaponifiablematter were studied. The LD50 for M. peregrina was 113.4 mg/100 g b.wt. Repeated intraperitoneal injection of 1/20 and 1/10 LD50 (5.67 mg and 11.34 mg/100 g b.wt.) of defatted alcoholic extract of M. peregrina for 30 daysinduced significant decrease in serum glucose, liver enzymes and lipid components. M. peregrina administeredi.p., 30 min prior to carrageenan at the above doses significantly inhibited the rat paw oedema response. In acuteM. peregrina exhibited markedanalgesic properties. In addition, M. peregrina administered at time of indomethacin injection inhibited thedevelopment of gastric lesions in rats.
Phytochemical and Biological Studies on Verbascum sinaiticum Growing in Egypt
Samia M. Mahmoud,Nahla S. Abdel-Azim,Abdelaaty A. Shahat,Shams I. Ismail,Faiza M. Hammouda 한국생약학회 2007 Natural Product Sciences Vol.13 No.3
aerial parts of Verbascum sinaiticum Benth. (Scrophulariaceae) yielded two iridoids that wereidenified as ajugol 3 and aucubin 4. Also, investigation of the flavonoid constituents revealed the isolation andidentification of luteolin 1 and chrysoeriol-7-glucoside 2. All the isolated compounds were identifid by spectrosco-picmethods (UV, MS, 1H-NMR and 13C-NMR) and in comparison with the literature data. Both alcohol andmethylene chloride/methanol extracts (1 : 1) exhibited a hepatoprotective effect by CCl4challenge test. KeywordsFlavonoids, Hepatoprotection, Iridoides, Verbascum sinaiticum
Analysis of weld-induced residual stresses and distortions in thin-walled cylinders
Naeem Ullah Dar,Ejaz M. Qureshi,M.M.I Hammouda 대한기계학회 2009 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.23 No.4
Circumferential weld specifically in thin-walled structures is a common joint type in the fabrication of structural members in aerospace, aeronautical and pressure vessel industries. This type of weld joint suffers various types of weld-induced residual stress fields (hoop and axial) and deformation patterns (axial shrinkage, radial shrinkage). These imperfections have negative effects on fabrication accuracies and result in low strength welded structures that can lead to premature failures. To precisely capture the distortions and residual stresses, computational methodology based on three-dimensional finite element model for the simulation of gas tungsten arc welding in thin-walled cylinders is presented. Butt-weld geometry with single "V" for a 300 mm outer diameter cylinder of 3 mm thick is used. The complex phenomenon of arc welding is numerically solved by sequentially coupled transient, non-linear thermo-mechanical analysis. The accuracy of both the thermal and structural models is validated through experiments for temperature distribution, residual stresses and distortion. The simulated result shows close correlation with the experimental measurements.