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Secondary Squamous Cell Carcinoma of the Oral Cavity after Nasopharyngeal Carcinoma
Liyuan Dai,Qigen Fang,Peng Li,Junfu Wu,Xu Zhang 대한암학회 2020 Cancer Research and Treatment Vol.52 No.1
Purpose The main goal of this study was to analyze the prognosis of secondary oral squamous cell carcinoma (SCC) with a comparison with sporadic oral SCC by a matched-pair design. Materials and Methods Records of patients with surgically treated primary oral SCC were reviewed, and a total of 83 patients with previous history of radiotherapy for nasopharyngeal carcinoma (NPC) were retrospectively enrolled. A matched-pair study was performed, each NPC survivor was matched with two sporadic oral SCC patients by age, sex, primary tumor site, adverse pathologic characteristics, disease stage, neck node status, and tumor stage. The overall survival (OS) and disease-specific survival (DSS) rates were calculated by the Kaplan-Meier method; independent prognostic factors were evaluated by the Cox proportional hazards method. Results Compared with sporadic oral SCC patients, NPC survivors were less likely to be smokers (p=0.004), perineural invasion and lymphovascular invasion were more common in NPC survivors (both p < 0.001). The 5-year OS and DSS rates in NPC survivors were 47% and 54%, respectively; the 5-year OS and DSS rates in sporadic oral SCC patients were 62% and 67%, respectively; the difference was significant (both p < 0.05). In survival analysis, disease stage remained to be independent prognostic factor for both the OS and DSS. Conclusion NPC survivors had worse OS and DSS than sporadic oral SCC patients, NPC survivors were less likely to be smokers, but had higher opportunity of perineural invasion and lymphovascular invasion. Disease stage was the most important predictor for the survival in NPC survivors.
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Zhang Yuan,Shao Junpeng,Zhang Liyuan,Dai Ye,Lai Yinan 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.10
This paper introduces the components and functions of institution aiming at docking capture link of the small satellite manipulator end executor. Putting forward to Euler method and quaternion as the theoretical basis, kinetics of grasping institution the relative position and attitude are modeling and analyzed. The axial tilt grab conditions of the simulation analysis are finished by the ADAMS software. The results of the simulation analysis for the relative position and velocity and the hand-grasp collision force are concluded.
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