The effect of bacterial cellulose membrane compared with collagen membrane on guided bone regeneration

So-Hyoun Lee,Youn-Mook Lim,Sung In Jeong,Sung-Jun An,Seong-Soo Kang,Chang-Mo Jeong,Jung-Bo Huh 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.6

PURPOSE. This study was to evaluate the effects of bacterial cellulose (BC) membranes as a barrier membrane on guided bone regeneration (GBR) in comparison with those of the resorbable collagen membranes. MATERIALS AND METHODS. BC membranes were fabricated using biomimetic technology. Surface properties were analyzed, Mechanical properties were measured, in vitro cell proliferation test were performed with NIH3T3 cells and in vivo study were performed with rat calvarial defect and histomorphometric analysis was done. The Mann-Whitney U test and the Wilcoxon signed rank test was used (α<.05). RESULTS. BC membrane showed significantly higher mechanical properties such as wet tensile strength than collagen membrane and represented a three-dimensional multilayered structure cross-linked by nano-fibers with 60 % porosity. In vitro study, cell adhesion and proliferation were observed on BC membrane. However, morphology of the cells was found to be less differentiated, and the cell proliferation rate was lower than those of the cells on collagen membrane. In vivo study, the grafted BC membrane did not induce inflammatory response, and maintained adequate space for bone regeneration. An amount of new bone formation in defect region loaded with BC membrane was significantly similar to that of collagen membrane application. CONCLUSION. BC membrane has potential to be used as a barrier membrane, and efficacy of the membrane on GBR is comparable to that of collagen membrane.

The effect of bacterial cellulose membrane compared with collagen membrane on guided bone regeneration

Lee, So-Hyoun,Lim, Youn-Mook,Jeong, Sung In,An, Sung-Jun,Kang, Seong-Soo,Jeong, Chang-Mo,Huh, Jung-Bo The Korean Academy of Prosthodonitics 2015 The Journal of Advanced Prosthodontics Vol.7 No.6

PURPOSE. This study was to evaluate the effects of bacterial cellulose (BC) membranes as a barrier membrane on guided bone regeneration (GBR) in comparison with those of the resorbable collagen membranes. MATERIALS AND METHODS. BC membranes were fabricated using biomimetic technology. Surface properties were analyzed, Mechanical properties were measured, in vitro cell proliferation test were performed with NIH3T3 cells and in vivo study were performed with rat calvarial defect and histomorphometric analysis was done. The Mann-Whitney U test and the Wilcoxon signed rank test was used (${\alpha}<.05$). RESULTS. BC membrane showed significantly higher mechanical properties such as wet tensile strength than collagen membrane and represented a three-dimensional multilayered structure cross-linked by nano-fibers with 60 % porosity. In vitro study, cell adhesion and proliferation were observed on BC membrane. However, morphology of the cells was found to be less differentiated, and the cell proliferation rate was lower than those of the cells on collagen membrane. In vivo study, the grafted BC membrane did not induce inflammatory response, and maintained adequate space for bone regeneration. An amount of new bone formation in defect region loaded with BC membrane was significantly similar to that of collagen membrane application. CONCLUSION. BC membrane has potential to be used as a barrier membrane, and efficacy of the membrane on GBR is comparable to that of collagen membrane.

[PE-0056] Natural variation in total phenol and total flavonoid content of maize varieties cultivated under different environment conditions

Hyoun-Min Park(Hyoun-Min Park),Myeong-Ji Kim(Myeong-Ji Kim),So Ra Jin(So Ra Jin),Min Ho Lee(Min Ho Lee),Yun-Young Kang(Yun-Young Kang),Oh Suk Yu(Oh Suk Yu),Eun-Ha Kim(Eun-Ha Kim),Sang-Gu Lee(Sang-Gu L 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

Fundamental understandings of mesh process and various formats of digital data in digital dentistry

Lee So-Hyoun,Jung Chang-Mo,Yoon Mi-Jung,Huh Jung-Bo,Lee Hyeonjong 대한치과이식(임프란트)학회 2021 The Korean Academy of Implant Dentistry Vol.40 No.1

Clinicians manage three-dimensional (3D) data in routine practice in the era of digital dentistry. Fundamental knowledge of digital data beyond the user’s manual provided by the companies is needed to understand and handle the 3D data in clinics. The 3D data used in the clinic are acquired by scanners and processed using a step-by-step procedure. A point cloud is an initial form of raw data. The data are then filtered, and a triangle mesh is generated. The meshes could be exported in various file formats. This fundamental knowledge would be helpful for clinicians in daily practice.

The Mechanical Properties and Biometrical Effect of 3D Preformed Titanium Membrane for Guided Bone Regeneration on Alveolar Bone Defect

Lee, So-Hyoun,Moon, Jong-Hoon,Jeong, Chang-Mo,Bae, Eun-Bin,Park, Chung-Eun,Jeon, Gye-Rok,Lee, Jin-Ju,Jeon, Young-Chan,Huh, Jung-Bo Hindawi 2017 BioMed research international Vol.2017 No.-

<P>The purpose of this study is to evaluate the effect of three-dimensional preformed titanium membrane (3D-PFTM) to enhance mechanical properties and ability of bone regeneration on the peri-implant bone defect. 3D-PFTMs by new mechanically compressive molding technology and manually shaped- (MS-) PFTMs by hand manipulation were applied in artificial peri-implant bone defect model for static compressive load test and cyclic fatigue load test. In 12 implants installed in the mandibular of three beagle dogs, six 3D-PFTMs, and six collagen membranes (CM) randomly were applied to 2.5 mm peri-implant buccal bone defect with particulate bone graft materials for guided bone regeneration (GBR). The 3D-PFTM group showed about 7.4 times higher mechanical stiffness and 5 times higher fatigue resistance than the MS-PFTM group. The levels of the new bone area (NBA, %), the bone-to-implant contact (BIC, %), distance from the new bone to the old bone (NB-OB, %), and distance from the osseointegration to the old bone (OI-OB, %) were significantly higher in the 3D-PFTM group than the CM group (<I>p</I> < .001). It was verified that the 3D-PFTM increased mechanical properties which were effective in supporting the space maintenance ability and stabilizing the particulate bone grafts, which led to highly efficient bone regeneration.</P>

현대장신구의 발생과 그 배경-1920~50년대 스튜디오 장신구를 중심으로-

이소현 ( So Hyoun Lee ) 한국기초조형학회 2015 기초조형학연구 Vol.16 No.5

이 논문은 1950 년대에 등장한‘현대장신구’의 근원적 배경에 대한 역사적인 연구이다. 장신구는 일반적으로 인체를 장식하고 돋보이게 하는 도구로 존재해왔으나, 오늘날‘현대장신구’라고 불리는 장신구는 작가적 표현을 위한 예술품으로인식된다. 이러한 현대장신구의 특성이 발현된 시점과 그 발생 요인을 분석하는 것이 본 연구의 목적이다. 장신구의 현대적인 성격은 1920 년대 유럽에서 외부적 자극을 통해 형성되기 시작했다고 볼 수 있다. 첫째, 1 차 세계대전으로 신분사회가 무너진 상황을 들 수 있는데, 장신구 착용 행위가 계급을 넘어 보편화되며 장신구에 대한 인식이 현대적으로 변화되었기 때문이었다. 둘째로, 고도화된 기계문명이 장신구의 형태적 변화를 유도하였다. 이는 당대 사물 형태에 반영되었던기하학적인 조형요소와 공업용 신재료가 장신구에도 적용된 덕분이었다. 마지막으로, 제 2 차 세계대전을 기점으로 현대장신구는 모던 아트를 수용하며 새 국면을 맞았다. 장신구 작가들은 모던 아트를 영감의 원천으로 삼았고 현대장신구는미술관에서 전시되며 예술의 한 형태로 받아들여졌다. 한편, 이렇게 등장한 현대장신구는 1940 년대 전후에 내부적인움직임을 통해서 정체성을 확립하였다. 먼저, 장신구 작가들은 제작방식을 현대화하고 새로운 형태의 현대장신구를 만들었다. 이들은 길드나 공장이 아닌 개인 작업공간에서 예술가 artist-jeweler 의 입장으로 만든‘스튜디오 장신구 Studio Jewelry’를 발전시켰다. 또한, 대학과 사회교육, 관련 협회 등 제도적 차원에서 장신구 창작 지원 활동이 증가하여 현대장신구는 학문적으로도 인정받고 저변을 확대할 수 있었다. 이러한 배경에서 마침내 현대장신구는 1960 년대에 독립적인예술분야로 자리매김하였다. This paper presents a historical analysis of the beginnings of modern jewelry, which began in the 1950s. In contrast with earlier jewelry, modern jewelry is considered an art form unto itself. This study examines the background that served as a catalyst for the evolution of jewelry making. Largely, because of three external factors, the quality of modern jewelry developed in Europe in the 1920s. First, the collapse of hierarchical society during World War I created a widespread jewelry-wearing culture and changed the concept of jewelry. Second, the highly developed machine civilization influenced the shape of jewelry; because of geometric elements and industrial materials not only applied to daily necessaries but to jewelry as well. Third, modern jewelry incorporated the concepts and ideologies associated with visual Modernism. Jewelers were inspired by modern art, and jewelry was adapted as art, thereby making it the subject of major exhibitions. Around 1940, modern jewelry developed its own identity through the rise of internal movements. Jewelers modernized how they made jewelry and created a new form of jewelry, studio jewelry. This type of jewelry was not produced by guilds or in factories but was created in personal workspaces by artist-jeweler. Finally, institutions that supported modern jewelry making, such as universities, social education centers, and professional associations, began expanding scholarly and cultural influence of modern jewelry. With all this in place, by the 1960s modern jewelry was seen as an established art form internationally.

서구 근대기 전시제도와 공예에 대한 인식의 변화 연구

이소현 ( Lee So Hyoun ) 한국기초조형학회 2016 기초조형학연구 Vol.17 No.4

‘전시exhibition’문화는 18세기 중반 공공 뮤지엄의 탄생과 함께 근대적인 제도로 발전하였다. 공공 뮤지엄과 만국박람회 등의 근대 전시공간은 선별된 전시물을 보여주며 대중적 계몽을 추구하는 권위적 장소였고, 19세기 중반에 이르러 공예품이 그러한 공간에 등장하게 되었다. 산업혁명 이후 일상적 사물로서의 역할을 양산된 산업제품에 넘겨주었던 공예품은 전시장에서는 오히려 일상적 사물의 우수한 본보기로써 전시되었다. 이점에 주목하여, 근대적인 전시장에 공예품이 전시되기 시작한 초기의 상황을 살펴보고 이후 현대공예가 전개되면서 전시제도가 수행한 역할과 공예에 대한 인식 변화에 끼친 영향을 추적하는 데에 연구의 목적을 두었다. 공예품이 처음으로 공공 전시장에 진열되어 대중에게 대대적으로 노출된 장소는 만국박람회장이었다. 만국박람회는 유럽과 미국 각지의 장식미술 및 공예협회의 결성과 이들의 전시 개최를 유도하였을 뿐 아니라, 각국의 뮤지엄이 과거의 공예품과 현대공예품을 두루 전시하도록 만드는 계기가 되었다. 이후 박람회와 협회, 뮤지엄은 각기 다른 성격의 공예전시를 기획하였다. 박람회의 공예전시는 고급 상점의 진열 방식을 적용하여 공예품을 훌륭한 상품으로 인식하게 만들었고, 공예 관련 협회의 전시는 상품이면서 회원들의 작품이기도 한 공예품의 특성을 드러냈다. 한편 뮤지엄에서는 공예품을 고급 문화를 전달하는 질 높은 상품으로 다루었다. 결론적으로, 20세기 전후의 공예 전시장은 고급 상점과 같이 꾸며져, 좋은 물건의 견본을 널리 홍보하기 위해 기획된 공간이었다. 그곳에서 대중은 전시된 공예품을 통해 생활 및 소비 취향을 학습하였다. 본 연구를 통해, 공예품이 전시제도에 진입하여 일반 양산제품과는 차별화된 위상을 얻었고, 대중 생활문화의 발전과 소비시장의 활성화를 위한 소재로 활용되었음을 확인할 수 있었다. Exhibition culture has been institutionalized as a modern exhibition system along with the emergence of public museum around the middle of 18th century. Modern exhibition system such as international exhibitions and public museums started to be recognized as a place of authority designed to enlighten the public by displaying only selected objects. By the middle of 19th century, craftworks could possibly enter this modern exhibition system. Even though mass products replaced craftworks``practical functions in everyday life after the Industrial Revolution, craftworks were able to earn a reputation as an ideal model of articles for daily use in this system. International Expositions played a leading role in displaying crafts and exposing them to the public for the first time. International Expositions successfully induced the establishment of several decorative arts and crafts societies and the organization of many society exhibitions in Europe and North America. Also, influenced by international expositions and society exhibitions, public museums started to hold various craft exhibitions. Along with this transition, International expositions, societies and museums started to organize craft exhibitions with their own ways. International expositions, for instance, applied luxurious retail display to make visitors recognize craftworks as attractive commodities. Society exhibitions emphasized the meaning of craftworks not only as commodities but also as artworks of society members while museums paid attention to the value of craftworks as high quality products which conveyed the high culture of living. Consequently, craft exhibition spaces designed like luxurious department stores in around 20th Century provided a great opportunity for craftworks to be evaluated as a standard of excellent commodities. In these spaces, craftworks could be also utilized as the public educational equipment for the better taste of living. By examining the role of modern exhibition system in modern crafts, this study focuses on what has led crafts``change in status and how craftworks have affected the development of public living culture and the revitalization of public consumption demands.

Comparison of the accuracy of digitally fabricated polyurethane model and conventional gypsum model

So-Yeun Kim,So-Hyoun Lee,Seong-Keun Cho,Chang-Mo Jeong,Young-Chan Jeon,Mi-Jung Yun,Jung-Bo Huh 대한치과보철학회 2014 The Journal of Advanced Prosthodontics Vol.6 No.1

PURPOSE. The accuracy of a gypsum model (GM), which was taken using a conventional silicone impression technique, was compared with that of a polyurethane model (PM), which was taken using an iTero™ digital impression system. MATERIALS AND METHODS. The maxillary first molar artificial tooth was selected as the reference tooth. The GMs were fabricated through a silicone impression of a reference tooth, and PMs were fabricated by a digital impression (n=9, in each group). The reference tooth and experimental models were scanned using a 3 shape convinceTM scan system. Each GM and PM image was superimposed on the registered reference model (RM) and 2D images were obtained. The discrepancies of the points registered on the superimposed images were measured and defined as GM-RM group and PM-RM group. Statistical analysis was performed using a Student’'s T-test (α=0.05). RESULTS. A comparison of the absolute value of the discrepancyrevealed a significant difference between the two groups only at the occlusal surface. The GM group showed a smaller mean discrepancy than the PM group. Significant differences in the GM-RM group and PM-RM group were observed in the margins (point a and f), mesial mid-axial wall (point b) and occlusal surfaces (point c and d). CONCLUSION. Under the conditions examined, the digitally fabricated polyurethane model showed a tendency for a reduced size in the margin than the reference tooth. The conventional gypsum model showed a smaller discrepancy on the occlusal surface than the polyurethane model.

Natural variation in functional components of rice by environmental and genetic factors

Hyoun-min Park,Jung-won Jung,So Ra Jin,Eun-ha Kim,Sang-gu Lee,Soo-yun Park,Seon-woo Oh 한국육종학회 2023 한국육종학회 공동학술발표집 Vol.2023 No.-

Effect of microneedle on the pharmacokinetics of ketoprofen from its transdermal formulations.

So, Jae-Woo,Park, Hyoun-Hyang,Lee, Seung S,Kim, Dong-Chool,Shin, Sang-Chul,Cho, Cheong-Weon Academic Press ; Taylor Francis 2009 DRUG DELIVERY Vol.16 No.1

<P>Non-invasive transdermal delivery using microneedle arrays was recently introduced to deliver a variety of large and hydrophilic compounds into the skin, including proteins and DNA. In this study, a microneedle array was applied to the delivery of a hydrophobic drug, ketoprofen, to determine if transdermal delivery in rats can be improved without the need for permeation enhancers. The ability of a microneedle to increase the skin permeability of ketoprofen was tested using the following procedure. A microneedle array was inserted into the lower back skin of a rat using a clip for 10 min. Subsequently, 24 mg/kg of a ketoprofen gel was loaded on the same site where the microneedle had been applied. Simultaneously, the microneedle was coated with 24 mg/kg of a ketoprofen gel, and inserted into the skin using a clip for 10 min. As a negative control experiment, only 24 mg/kg of the ketoprofen gel was applied to the shaved lower back of a rat. Blood samples were taken at the indicated times. The plasma concentration (C(p)) was obtained as a function of time (t), and the pharmacokinetic parameters were calculated using the BE program. The group loaded with the microneedle coated with ketoprofen gel showed a 1.86-fold and 2.86-fold increase in the AUC and C((max)) compared with the ketoprofen gel alone group. These results suggest that a microneedle can be an ideal tool for transdermal delivery products.</P>