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        Soil Interaction of H-shaped Steel-RC Stepped Pile of Integral Abutment Bridge: Experimental Evaluation

        Yizhou Zhuang,Kun-Sheng Song,Said M. Easa,Yong-Qing Song 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.3

        The reinforced concrete piles (RC) in integral abutment bridges (IABs) are challenging to meet the longitudinal deformation of bridges with significant lateral stiffness. The H-shaped steel (HS) piles are costly and prone to corrosion. This paper proposes a new form of pile comprised of HS and RC piles in series to meet the longitudinal deformation demand of IABs. Tests were conducted for one HS pile under reciprocating low-cycle pseudo-static test and two HS-RC stepped piles with different bending stiffness ratios of HS/RC (0.25 and 0.5) using the HS-RC pile test model,. The influence of the stiffness ratio on the mechanical behavior of stepped pile-soil was studied. The mechanical behavior of the stepped pile was also compared with single HS and RC piles. and the applicability of the m and p-y curve methods to the calculation of horizontal displacement of stepped pile is discussed. The results show that the elastic deformation range of the HS pile is 2 mm to 25 mm, and its horizontal deformation capacity and bearing capacity are excellent. As the stiffness ratio increases, the stepped pile-soil system's yield displacement and yield load increased. The stiffness ratio has no significant effect on the failure mode of the piles. The hysteretic ring of the stepped pile shows a squeezing shape at the initial loading stage, but becomes a full spindle in the later loading stage. The stepped pile shows an excellent energy consumption effect and a horizontal deformation ability, indicating it is suitable for IABs. The m method has better accuracy only up to 2 mm displacement, while the p-y curve method still has higher accuracy within 15 mm.

      • Non-Association of IL-16 rs4778889 T/C Polymorphism with Cancer Risk in Asians: a Meta-analysis

        Xu, Lin-Lin,Song, Zhi-Chun,Shang, Kun,Zhao, Li-Qin,Zhu, Zhan-Sheng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

        The IL-16 rs4778889 T/C polymorphism is associated with cancer risk. However, the results are conflicting. We performed this meta-analysis to derive a more precise estimation of the relationship. A comprehensive literature search was performed using PubMed, Embase and Web of Science databases. Odds ratio (OR) and 95% confidence interval (CI) were used to assess the strength of association. A total of 6 studies including 1,603 cases and 2,342 controls were identified. With all studies involved, results showed no statistically significant association between IL-16 rs4778889 T/C polymorphism and cancer risk (CC vs. CT+TT: OR=0.74, 95%CI:0.55-1.02, $P_h=0.15$; CC+CT vs. TT: OR=0.89, 95%CI: 0.72-1.10, $P_h=0.03$; CC vs. TT: OR=0.73, 95%CI: 0.53-1.00, $P_h=0.08$; CT vs. TT: OR=0.91, 95%CI: 0.79-1.05, $P_h=0.08$; C vs. T: OR=0.89, 95%CI: 0.74-1.07, $P_h=0.02$). In addition, the results were not changed when studies were stratified by cancer type. However, to verify our findings, it is essential to perform more well-designed studies with larger sample sizes in the future.

      • Clinical and Pathological Factors Related to the Prognosis of Chinese Patients with Stage Ⅰb To Ⅱb Cervical Cancer

        Xie, Xiu-Zhen,Song, Kun,Cui, Baoxia,Jiang, Jie,Zhang, You-Zhong,Wang, Bo,Yang, Xing-Sheng,Kong, Bei-Hua Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11

        Objective: The aim of this retrospective study is to analyze the clinical and pathological factors related to the prognosis of Chinese patients with stage Ib to IIb cervical cancer. Methods and Results: 13 clinical pathological factors in 255 patients with stage Ib to IIb cervical cancer undergoing radical hysterectomy and systematic lymphadenectomy were analyzed to screen for factors related to prognosis. The cumulative 5-year survival of the 255 patients was 75.7%. The result of the univariate analysis suggested that clinical stage, cell differentiation, depth of cervical stromal invasion, parametrial tissue involvement, and lymph node metastasis were prognostic factors for patients with stage Ib to IIb cervical cancer (P<0.05). Compared with cases with involvement of iliac nodes, obturator nodes, or inguinal lymph nodes, cases with metastasis to the common iliac lymph nodes had a poorer prognosis (P<0.05). Cases with involvement of four or more lymph nodes had a poorer prognosis than those with involvement of three or fewer lymph nodes (P<0.05). Using multivariate Cox proportional hazards model regression analysis, non-squamous histological type, poor differentiation, parametrial tissue involvement, and outer 1/3 stromal invasion were found to be independently related to patients poor prognosis (P<0.05). Conclusion: Non-squamous histological type, poor cell differentiation, parametrial tissue involvement, and outer 1/3 stromal invasion are the independent poor prognostic factors for patients with stage Ib to IIb cervical cancer.

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