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- 저자 : Khaled Omar Mohamed (검색결과 3 건)
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Osama Eldamshety,Sherif Kotb,Ashraf Khater,Waleed Elnahas,Sameh Roshdy,Mohamed S. Zahi,Hend M.H. Rashed Elkalla,Omar Farouk,Ahmed Senbel,Adel Fathi,Emad-Eldeen Hamed,Khaled Abdelwahab,Islam A. Elzahby 대한대장항문학회 2020 Annals of Coloproctolgy Vol.36 No.3
Purpose: The study aims to assess the functional outcome of anal sphincter-sparing procedures (SSP) with total mesorectal excision (TME) for anorectal adenocarcinoma. Methods: In a multicentric, prospective, single-group study in the period between December 2012 and November 2017, 93 patients presented with anorectal adenocarcinoma were included in the study. Sixty-nine patients underwent SSP with TME. SSP included the combined approach of transabdominal TME with intersphincteric resection (ISR) or transanal transabdominal TME. Using the per anal examination scoring system (PASS), postoperative anal function was assessed after 1 year. Results: Bowel motility time was 50±19 hours. The time needed for narcotic analgesia was 54±18.8 hours. Mean hospital stay was 15.4±10.25 days. Incidence of evident fecal incontinence after ISR is 10.6% (7 of 67 cases). The PASS findings of 69 cases are as follows: extremely hypotonic 8.6% (6 cases), slightly hypotonic 26.1% (18 cases), normal tone 58% (40 cases), slightly stenotic 3 cases (4.3%), or occluded 2.9% (2 cases). Urinary dysfunction occurred in 1 case (1.4%). Temporary diversion was performed in 61 patients (87.1%). Conclusion: Sphincter preservation with TME for anorectal adenocarcinoma helps avoid permanent stoma and provides reasonable functional outcomes. PASS is a new application for postoperative assessment of anal function.
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KhaledA.M.Abouzid,Nadia A. Khalil,Eman M. Ahmed,Khaled Omar Mohamed 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.1
A series of novel substituted 3,6-disubstitutedpyridazines based on the structure of vatalanib (PTK787)were designed and synthesized. The cytotoxicity of thefinal compounds was tested in vitro on HT-29 colon cancercell line. Compounds 2a and 2b with 4-chlorophenylaminomoiety, exerted the highest cytotoxic activity with IC50values equal to 15.3 and 3.9 lM respectively. The mostpromising compound, 2b, was found to be about fivefoldmore active than vatalanib against HT-29 colon cancer cellline.
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Mohanad S. Eid,I.I. Bondouk,Hosam M. Saleh,Khaled M. Omar,M.I. Sayyed,Ahmed M. El-Khatib,Mohamed Elsafi 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.4
The aim of this work is to study the radiation shielding properties of cement samples with waste glassincortated into its composition. The mass attenuation coefficient (MAC) of the samples were experimentally determined to evaluate their radiation shielding ability. The experimental coefficient wasevaluated using NaI detector for gamma energies between 59.53 keV and 1408.01 keV using differentradioactive point sources Am-241, Eu-152, Co-60, and Cs-137, and the gamma transmission parametershalf-value layer, mean free path, and transmission factor were calculated. The theoretical coefficient ofthe composites was determined using Geant4 and XCOM software. The results were also comparedagainst Geant4 and XCOM simulations by calculating the relative deviation between the values todetermine the accuracy of the results. In addition the mechanical properties (including Compressive andporosity) as well as the thermogravimetric analysis were tested for the present samples. Overall, it wasconcluded that the cement sample with 50% waste glass has the greatest shielding potential for radiationshielding applications and is a useful way to reuse waste glass.
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