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      • KCI등재

        Effectiveness and Approach of Rehabilitation in Patients With Acute Heart Failure: A Review

        Kensuke Ueno,Hidehiro Kaneko,Hidetaka Itoh,Norifumi Takeda,Hiroyuki Morita,Katsuhito Fujiu,Kentaro Kamiya,Issei Komuro 대한심장학회 2022 Korean Circulation Journal Vol.52 No.8

        Acute heart failure is associated with high mortality and frequent rehospitalization, resulting in enormous healthcare costs and declining physical function, activities of daily living, and quality of life. Cardiac rehabilitation has been recommended as one of the non-pharmacologic treatments for patients with heart failure. However, much of the evidence for cardiac rehabilitation interventions reported to date has been limited to chronic heart failure. In recent years, the effectiveness of rehabilitation intervention in patients with acute heart failure has been reported, led by the Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial. This review overviews the recent evidence of rehabilitation in patients with acute heart failure.

      • SCOPUSKCI등재

        Kuroshio Observation Program: Towards Real-Time Monitoring the Japanese Coastal Waters

        Ostrovskii, Alexander,Kaneko, Arata,Stuart-Menteth, Alice,Takeuchi, Kensuke,Yamagata, Toshio,Park, Jae-Hun,Zhu, Xiao Hua,Gohda, Noriaki,Ichikawa, Hiroshi,Ichikawa, Kaoru,Isobe, Atsuhiko,Konda, Masanor Korea Institute of Ocean Science Technology 2001 Ocean and Polar Research Vol.23 No.2

        The challenge of predicting the Japanese coastal ocean motivated Frontier Observational Research System for Global Change (FORSGC) and the Japan Marine Science and Technology Center (JAMSTEC) to start a multiyear observational programme in the upstream Kuroshio in November 2000. This field effort, the Kuroshio Observation Program (KOP), should enable us to determine the barotropic and baroclinic components of the western boundary current system, thus, to better understand interactions of the currents with mesoscale eddies, the Kuroshio instabilities, and path bimodality. We, then, will be able to improve modeling predictability of the mesoscale, seasonal, and inter-annual processes in the midstream Kuroshio near the Japanese main islands by using this knowledge. The KOP is focused on an enhanced regional coverage of the sea surface height variability and the baroclinic structure of the mainstream Kuroshio in the East China Sea, the Ryukyu Current east of the Ryukyu's, and the Kuroshio recirculation. An attractive approach of the KOP is a development of a new data acquisition system via acoustic telemetry of the observational data. The monitoring system will provide observations for assimilation into extensive numerical models of the ocean circulation, targeting the real-time monitoring of the Japanese coastal waters.

      • KCI등재후보

        Tissue factor expression is associated with recurrence in patients with non-metastatic colorectal cancer

        Hee Jae Jung,Hye Jin Kim,Kensuke Kaneko,Yoshihiro Kazama,Kazushige Kawai,Soichiro Ishihara,Gyu Seog Choi 대한종양외과학회 2018 Korean Journal of Clinical Oncology Vol.14 No.2

        Purpose: Previous studies have addressed the role of the hypercoagulable state in the pathogenesis of cancer progression and metastasis. In this study, we investigated the association between coagulation factors, including tissue factor (TF) expression, platelet count, and fibrinogen level, and disease recurrence in patients with non-metastatic colorectal cancer. Methods: Patients who underwent curative resection for stage II or III colorectal cancer between 2000 and 2007 were included in this study. Data from a prospectively maintained database were retrospectively reviewed. TF expression was determined by immunohistochemistry using an anti-TF monoclonal antibody. The Kaplan-Meier method was used to estimate 5-year disease-free survival. Results: TF was highly expressed in 257 of 297 patients (86.5%). TF expression was not significantly associated with the platelet counts (P=0.180) or fibrinogen level (P=0.281). The 5-year disease-free survival rate was lower in patients with high TF expression than in patients with low TF expression (72.3% vs. 83.9%, P=0.074). In Cox hazard analysis, high TF expression was an independent risk factor for tumor re�currence (hazard ratio [HR] 2.446; 95% confidence interval [CI], 1.054–5.674; P=0.037). Undifferentiated histologic type (HR, 2.911; 95% CI, 1.308–6.481; P=0.009), venous invasion (HR, 2.784; 95% CI, 1.431–5.417; P=0.003), and lymph node metastasis (HR, 2.497; 95% CI, 1.499–4.158; P<0.001), were also significantly associated with disease recurrence. Conclusion: TF expression is associated with a recurrence in patients with non-metastatic colorectal cancer. However, further studies are re�quired to clarify the underlying mechanisms relating TF expression with oncologic outcomes and its potential role as a therapeutic target.

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