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- 저자 : K.B Santosh Babu (검색결과 3 건)
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Thokchom Bothe,Bhavi Santosh Mallikarjun,Abbigeri Megha B.,Shettar Arun K.,Yarajarla Ramesh Babu 한국탄소학회 2023 Carbon Letters Vol.33 No.4
Medicinal plant-derived carbon dots are eco-friendly and possess therapeutic properties. Among the medicinal plants studied throughout the world, Centella asiatica (L.) Urb. is known for its medicinal values, especially its neuroceutical and cogniceutical properties. This work discusses the green synthesis of carbon dots (CDs) using C. asiatica leaves as the carbon source via fast and cost-effective microwave-assisted method, and its physico-chemical characterization via UV–visible, fluorescence and FTIR spectrometry, XRD, SEM, AFM, TEM, SAED, EDX and zeta potential analyses. The study revealed quasi-spherical CDs having size ~ 3–6 nm, polycrystalline nature, and presence of various functional groups like –COOH, –H, =CH2 and C–O–C with UV absorption peaks at 213 and 322 nm. Interestingly, the C. asiatica-derived CDs exhibited blue fluorescence under UV with maximum emission wavelength of 460 nm when excited at 400 nm. Further, these CDs were evaluated for their biological applications, which uncovered their potential in therapeutics such as antimicrobial properties against both Gram-positive and Gram-negative bacteria at a dose of 10 μg, strong antioxidant activity with IC50 values of 165.28 and 128.48 μg mL−1 in DPPH and H2O2 assays, respectively, and profound anti-inflammatory activity with IC50 value of 106.20 μg mL−1 in protein denaturation assay. The CDs were also assessed for cytotoxicity using whole blood cells and were found to be safe for in vitro administration. Thus, the C. asiatica-derived CDs can be exploited for their potent biomedicinal properties.
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Arur Anand,G. Kantharajan,P. Krishnan,K. Abdul Hakeem,K. Sai Santosh,Ch. Srinivasa Rao,Kuldeep K. Lal,S. B. Choudhury,C. Manjulatha,D. E. Babu 대한공간정보학회 2019 Spatial Information Research Vol.27 No.6
Planning aquaculture and fisheries activities in a reservoir requires knowledge of dynamics of water spread. We studied water spread dynamics of three reservoirs in the Godavari river basin, India using multi-temporal satellite imagery for the period 1990–2018 and developed a framework for mapping the spatial extent of water spread area (WSA) having potential for enclosure fish culture. The study showed that WSA of Nizamsagar reservoir in premonsoon season has declined from 108.11 to 99.34 km2 from phase I (1990–2006) to phase II (2007–2018), respectively and a similar trend was seen in Pocharam and Nallavagu reservoirs. For post monsoon seasons of the same time period, an increase in WSA was seen in Nizamsagar (133.75–144.14 km2) and Pocharam reservoirs (14.15-14.67 km2). Based on frequency of water presence during 2007–2018, WSA with potential for cage and pen culture was determined in Nizamsagar (31.04 km2) and Pocharam (2.87 km2) reservoirs. The study showed that both the reservoirs can accommodate maximum allowed number of cages (5000 and 500 cages respectively). We provide a decision matrix for location-specific selection of suitable culture methods and candidate species, which would aid in optimal utilization of the hitherto under-utilized reservoirs, especially in in situ data poor conditions. This study can be scaled up in the entire country with the help of academia/industry to prioritize reservoirs with potential for enclosure fish culture and plan appropriate interventions for reducing their yield gap.
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Delayed Spontaneous Thrombosis of Neglected Direct Carotid-Cavernous Fistula: A Case Report
Tiwari Sarbesh,Garg Pawan Kumar,Khera Pushpinder Singh,K.B Santosh Babu,Yadav Taruna,Sureka Binit 대한신경중재치료의학회 2020 Neurointervention Vol.15 No.2
Direct carotid-cavernous fistula (CCF) refers to direct communication between the cavernous portion of the internal carotid artery (ICA) and the cavernous sinus due to rent in the ICA, most commonly secondary to trauma. These are generally high-flow fistula and rarely resolve spontaneously. We report a case of a young male who developed features of direct CCF after trauma, was denied any treatment for 4 years, and then presented with spontaneous thrombosis of the fistula and a residual large pseudoaneurysm of the cavernous segment of the right ICA, which was subsequently managed with parent vessel occlusion.
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