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A Prospective Study of Anterior Segment Ocular Parameters in Anisometropia
Neha Singh,Jolly Rohatgi,Vinod Kumar 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.2
Purpose: The aim of this study was to investigate the differences in anterior segment ocular parameters inanisometropia >1 D. Methods: This study included 202 eyes of 101 subjects ranging from 10 to 40 years of age with anisometropiaof 1 D or more. The subjects were divided into groups according to anisomyopia, anisoastigmatism, andanisohypermetropia. After providing informed consent, each patient underwent a detailed ophthalmologicalexamination including cycloplegic refraction, best-corrected visual acuity, cover test, axial length (AL) measurementusing A-scan ultrasound biometer, keratometry, anterior chamber depth, and central corneal thicknessmeasurement. For each participant, the eye with greater refractive error was compared to the fellow eyevia paired t-tests. Correlations between parameters were studied using the Pearson correlation coefficient. Results: The average age of subjects was 21.7 ± 9.3 years. Of 101 subjects, 31 had anisomyopia; 42 had anisohypermetropia;and 28 had anisoastigmatism. A predisposition toward greater myopia in right eyes was noted inanisomyopia (24 of 31 subjects, 77%). The inter-ocular acuity difference was significant in all three groups (p < 0.01). As the degree of anisometropia increased, there was significant positive correlation in the difference in AL inmyopes (r = 0.863, p < 0.01) and hypermetropes (r = 0.669, p < 0.01) and the difference in corneal curvaturein anisoastigmatism (r = 0.564, p = 0.002) and hypermetropes (r = 0.376, p = 0.014). A significant positive correlationwas also present between the anterior chamber depth difference and refractive difference in hypermetropes(r = 0.359, p = 0.020). Conclusions: This study showed that anisomyopia is correlated only with anterior chamber differences. Anisohypermetropiais correlated with AL differences as well as corneal curvature difference and anterior chamberdepth difference. The amount of anisoastigmatism correlates only with corneal curvature difference.