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Francisco Javier Leyva-Jiménez,Jesús Lozano-Sánchez,Isabel Borrás-Linares,David Arráez-Román,Antonio Segura-Carretero 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.79 No.-
A manufacturing design and control of bioactive ingredients from Aloysia citriodora was performedapplying microwave-assisted extraction (MAE). Thus, a Response Surface Methodology based on CentralComposite Design 23 model was performed to monitor the matrix behavior. The factors were extractiontime, percentage of solvent and temperature. The chosen responses were extraction yield andphytochemicals recovery. The design allowed tofind the optimal conditions for each response and tovalidate them in order to attain high quality ingredients. These results pointed out that MAE is a noveltechnique which could be used to improve the new functional ingredient development.
Optimization of the extraction of phytochemicals from black mulberry (Morus nigra L.) leaves
Nataša Nastić,Isabel Borrás-Linares,Jesús Lozano-Sánchez,Jaroslava Švarc-Gajić,Antonio Segura-Carretero 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.68 No.-
This study aimed to compare the chemical composition of Morus nigra leaves extracts, obtained by maceration, accelerated solvent (ASE) and supercritical fluid extraction (SFE) under different extraction conditions. With regards to chemical composition, mainly phenolic acids and flavonoids were identified. HPLC–ESI–QTOF–MS allowed the identification of 13 new compounds reported in M. nigra leaves for the first time. ASE as a fast, green and innovative approach, seems to be the best choice for extracting compounds of different polarities within the shortest extraction time. The present study also highlights the potential application of M. nigra extracts as constituents of new added-value formulations.