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      • KCI등재
      • 健康人과 身體 疾患者와의 衣服行態에 關한 比較 分析 : 20,30代 女性을 中心으로 in Thrd & Fouth Decade of Age

        鄭惠洛 啓明大學校 生活科學硏究所 1985 科學論集 Vol.11 No.-

        1. 疾病의 有無와 가장 좋아하는 色相과는 0.25수준에서 關係가 있다. 그러나 행동으로 실천하는 과정인 가장 입고싶은 옷색과의 關係는 낮게 나타났다. 그리고 健康人集團 疾患者集團 보다 빨강색을 항상 選好했다. 疾患者集團은 健康人 集團보다 無彩色을 모든 경우에 選好했으며, 보라色을 좋아하고 또 입고 싶은 옷색으 로 꼽았으나 3%정도만이 實在로 많이 입는 것으로 나타났는데 이는 身體的 條件과 心理的 自信感의 결여때문인 것 같다. 2. 무늬의 選好度에 있어서는 두 집단간의 차이가 크지는 않으나 他集團보다 健康人 集團은 모든 경우에 自然무늬를 疾患者集團은 無地를 선호했다. 가장 많이 입는 무늬 는 集團間 구별없이 아주 큰 比率로 無地를 선택했다. 그리고 질병과의 相關은 가장 낮게 나타났다. 3. 疾病의 有無에 따른 材質의 選擇은 色相이나 무늬보다도 뚜렷하여 가장 입고 싶 은 材質과 가장 많이 입는 材質에서 相關이 있게 나타났다. 가장 좋아하는 材質은 綿, 가장 입고 싶은 材質은 絹과 knit, 가장 많이 입는 材質은 綿과 合纖이다. 集團間 차이점은 疾患者集團은 健康人集團보다 材質選擇에 일관된 態度를 보이며 모 든 경우에 絹을 더 선호했다. 材質의 選擇理由로서는 대체로 질환자 집단은 편하고 값싸며 옷맵씨가 좋기 때문에, 건강인집단은 衛生的이며 管理하기가 쉽기 때문이라는 것을 더 많이 들고 있다. 따라서 질환자집단이 外的인 面을 더 重視한다고 볼 수 있다. The purpose of this study is the analysis and comparison of clothing styles worn by people who are sick versus clothing styles worn by well people. The method of study used in this paper was the distribution of a questionnaire followed by a computer tablation of the survey results thus obtained. The results can be summarized as follows: 1. The correlation of ill people's color preferences to those preferences non-patients is at the level of 0.25, which was considered to be quite low. Healthy people consistently indicated a preference for the color red as well as fabric which is patterned or designed, whereas the majority of those who are sick prefer non-designed, plain fabrics in cool colors of green blue or violet, due probably to their physical condition and psychological outlook. Only 3% of the patients surveyed preferred the bright colors and highly designed materials. 2. In terms of pattern preferences, no major difference was noted between the two groups. Healthy people generally preferred patterns reflecting some aspect of a linen design whereas sick people preferred and absence of all pattern elements. In general, the overall fabric preference of both groups combined was for plain, non-patterned fabric. 3. In both the sick and the well groups of people surveyed, the fature which played the greatest role in choice of fabric was the nature of the material itself, rather than either color or design. The most frequently selected materials, by wearers choice, were cotton and knit. The most frequently worn materials in reality, however, were cotton and synthetic fibre. The reasons for choosing the above materials for patient use were practicality, comfort and appearance. At the same time, healthy people preferred fabrics which were easy to maintain and keep clean.

      • KCI등재
      • SCISCIESCOPUS

        Antimicrobial activities of LCB10-0200, a novel siderophore cephalosporin, against the clinical isolates of <i>Pseudomonas aeruginosa</i> and other pathogens

        Oh, Sang-Hun,Park, Hee-Soo,Kim, Hye-Shin,Yun, Jeong-Yul,Oh, Kyuman,Cho, Young-Lag,Kwak, Jin-Hwan ELSEVIER 2017 INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS Vol.50 No.6

        <P><B>Abstract</B></P> <P>Infections caused by multidrug-resistant bacteria, including <I>Pseudomonas aeruginosa</I>, are threatening public health worldwide. Therefore, a novel antibacterial agent is needed to treat these infections. Here, we investigated the in vitro and in vivo activities of a novel siderophore-conjugated cephalosporin, LCB10-0200, against the clinical isolates of Gram-negative bacteria, including multidrug-resistant <I>P. aeruginosa</I>. In vitro susceptibility to LCB10-0200 was assessed by performing a two-fold agar dilution method, as described by the Clinical and Laboratory Standards Institute. LCB10-0200 showed the most potent antibacterial activity against <I>P. aeruginosa</I> clinical isolates, including β-lactamase-producing strains. Moreover, LCB10-0200 showed better antibacterial activity against recently isolated clinical isolates than its comparators, except colistin. The in vivo activity of LCB10-0200 was examined using four mouse models of systemic, thigh, respiratory tract, and urinary tract infections. LCB10-0200 was more effective than ceftazidime in treating systemic, thigh, respiratory tract, and urinary tract infections caused by drug-susceptible and drug-resistant <I>P. aeruginosa</I> strains in these mouse models. Thus, the potent in vitro and in vivo activities of LCB10–0200 observed in the present study indicate that it has the potential for treating infections caused by Gram-negative bacteria, including <I>P. aeruginosa</I>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> LCB10-0200 is a novel siderophore-cephalosporin conjugate. </LI> <LI> LCB10-0200 shows potent antibacterial activity against <I>P. aeruginosa</I>, including β-lactamase-producing strains. </LI> <LI> LCB10-0200 has potent in vivo activity and is more effective than ceftazidime against <I>P. aeruginosa</I>. </LI> <LI> LCB10-0200 is a promising novel cephalosporin candidate for treating infections caused by <I>P. aeruginosa</I>. </LI> </UL> </P>

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