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      • A Secure Fingerprinted Multimedia Distribution Using Social Network Analysis

        Cong-huan Ye,Zeng-gang Xiong,Yao-ming Ding,Xueming Zhang,Guangwei Wang,Fang Xu 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.4

        Collusion attack is a very effective attack for digital fingerprinting system. In order to remove or attenuate the fingerprint information hidden in fingerprinted content, a number of users produce a new colluded copy through their own fingerprinted copies. In this paper, we address a novel collusion-resisting desynchronization fingerprinting approach using social network analysis. The novelty of this paper is that collusion attack occurred in a multimedia social network community with high probability. Different from all existing works, with desynchronization model constructed upon social network, the original image is desynchronized to get many similar copies which are different from each other, and then they are assigned and distributed to subscribers according to social network analysis. Theory analysis shows that the presented desynchronization distribution method has significantly better performance than those existing distribution schemes. The experimental results also show that the average colluded images even with only two desynchronized copies have poor visual quality. And the visual quality of colluded images does not improve apparently with the increase of the number of copies.

      • Recursive Chaotic Desynchronized Fingerprint for Large Scale Distribution Using Social Network Analysis

        Cong-huan Ye,Zeng-gang Xiong,Yao-Ming Ding,Xueming Zhang,Guangwei Wang,Fang Xu 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.7

        Average collusion attack is a very effective attack for digital fingerprinting system. Moreover, the commercial value of the colluded content is often time-sensitive. The more profit the colluder will make from it when the colluded copy is distributed earlier. This paper presents a new collusion-resilience approach with recursive chaotic desynchronization and social network. It has processed chaotic transformations due to random image grid based on chaos. The experimental results show that collusion even with only two copies results in degradation of the image metric, even if those traitors try to resynchronization using image registration technology. However, it will take expensive computational cost to do that, and the visual quality is degraded expensively with the increase of the number of fingerprinted copies.

      • Metformin Down-regulates Endometrial Carcinoma Cell Secretion of IGF-1 and Expression of IGF-1R

        Zhang, Yu,Li, Meng-Xiong,Wang, Huan,Zeng, Zheng,Li, Xiao-Mao Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

        As metformin can inhibit endometrial carcinoma (EC) cell growth and the insulin growth factor (IGF) system is active in EC, the question of whether it can regulate endometrial carcinoma cell secretion of IGF-1 or expression of IGF-1 receptor (IGF-1R) is of interest. In this study, serum IGF-1 levels in EC patients were found to be comparable with that in the non EC patients (p>0.05). However, the IGF-1 level in the medium of cultured cells after treatment with metformin was decreased (p<0.05). IGF-1R was highly expressed in human endometrial carcinoma paraffin sections, but IGF-1R and phosphor-protein kinase B/protein kinase B (p-Akt/Akt) expression was down-regulated after metformin treatment (p<0.05). In summary, metformin can reduce the secretion of IGF-1 by Ishikawa and JEC EC cell lines and their expression of IGF-1R to deactivate downstream signaling involving the PI-3K/Akt pathway to inhibit endometrial carcinoma cell growth.

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        Antifungal activity of 3-acetylbenzamide produced by actinomycete WA23-4-4 from the intestinal tract of Periplaneta americana

        Xia Fang,Juan Shen,Jie Wang,Zhi-li Chen,Pei-bin lin,Zhi-yu Chen,Lin-yan Liu,Huan-xiong Zeng,Xiao-bao Jin 한국미생물학회 2018 The journal of microbiology Vol.56 No.7

        Actinomycetes are well-known for producing numerous bioactive secondary metabolites. In this study, primary screening by antifungal activity assay found one actinomycete strain WA23-4-4 isolated from the intestinal tract of Periplaneta americana that exhibited broad spectrum antifungal activity. 16S rDNA gene analysis of strain WA23-4-4 revealed close similarity to Streptomyces nogalater (AB045886) with 86.6% sequence similarity. Strain WA23-4-4 was considered as a novel Streptomyces and the 16s rDNA sequence has been submitted to GenBank (accession no. KX291006). The maximum antifungal activity of WA23-4-4 was achieved when culture conditions were optimized to pH 8.0, with 12% inoculum concentration and 210 ml ISP2 medium, which remained stable between the 5th and the 9th day. 3-Acetyl benzoyl amide was isolated by ethyl acetate extraction of WA23- 4-4 fermentation broth, and its molecular formula was determined as C9H9NO2 based on MS, IR, 1H, and 13C NMR analyses. The compound showed significant antifungal activity against Candida albicans ATCC 10231 (MIC: 31.25 μg/ml) and Aspergillus niger ATCC 16404 (MIC: 31.25 μg/ml). However, the compound had higher MIC values against Trichophyton rubrum ATCC 60836 (MIC: 500 μg/ml) and Aspergillus fumigatus ATCC 96918 (MIC: 1,000 μg/ml). SEM analysis showed damage to the cell membrane of Candida albicans ATCC 10231 and to the mycelium of Aspergillus niger ATCC 16404 after being treatment with 3-acetyl benzoyl amide. In conclusion, this is the first time that 3-acetyl benzoyl amide has been identified from an actinomycete and this compound exhibited antifungal activity against Candida albicans ATCC 10231 and Aspergillus niger ATCC 16404.

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