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Song, Juhye,Chun, Jaehwan,Kim, Ayoung,Jung, Hojae,Kim, Hyun Jong,Kim, Young-Jun,Jeong, Goojin,Kim, Hansu American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.40
<P>Dendritic growth of a Li metal anode during cycling is one of major issues to be addressed for practical application of Li metal rechargeable batteries. Herein, we demonstrate that surface modification of Li metal with a Na-containing SO<SUB>2</SUB> electrolyte can be an effective way to prevent dendritic Li growth during cell operation. The surface-modified Li metal anode exhibited no dendritic deposits even under a high areal capacity (5 mA h cm<SUP>-2</SUP>) and a high current density (3 mA cm<SUP>-2</SUP>), whereas the unmodified anode showed typical filamentary Li deposition. The surface-modified Li metal anode also demonstrated significantly enhanced electrochemical performance, which could be attributed to the newly formed Na-containing inorganic surface layer that exhibits uniform and dense properties. Consequently, surface modification with a Na-containing SO<SUB>2</SUB> inorganic electrolyte is suggested as one of the most effective ways to realize a highly stable Li metal anode with dendrite-free Li deposition for Li metal-based rechargeable batteries.</P> [FIG OMISSION]</BR>
Kim, Ayoung,Jung, Hojae,Song, Juhye,Kim, Hyun Jong,Jeong, Goojin,Kim, Hansu American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.9
<P>Herein, we have identified that lithium ions in an SO<SUB>2</SUB>-based inorganic electrolyte reversibly intercalate and deintercalate into/out of graphite electrode using ex situ X-ray diffraction and various electrochemical methods. X-ray photoelectron spectroscopy shows that the solid electrolyte interphase on the graphite electrode is mainly composed of inorganic compounds, such as LiCl and lithium sulfur-oxy compounds. Graphite electrode in SO<SUB>2</SUB>-based inorganic electrolyte has stable capacity retention up to 100 cycles and outstanding rate capability performance. This can be attributed to low interfacial impedance and high ionic conductivity of SO<SUB>2</SUB>-based inorganic electrolyte, which are superior to those of conventional organic electrolytes. Considering the remarkable rate capability and intrinsically nonflammable properties of the electrolyte, use of graphite and an SO<SUB>2</SUB> electrolyte will likely facilitate the development of advanced lithium-ion batteries.</P> [FIG OMISSION]</BR>
Cdk5 regulates N-cadherin-dependent neuronal migration during cortical development
Lee, Dong-Keun,Lee, Hojae,Yoon, Jiyoung,Hong, Sujeong,Lee, Yunjeong,Kim, Kyung-Tai,Kim, Jong Woon,Song, Mi-Ryoung Elsevier 2019 Biochemical and biophysical research communication Vol.514 No.3
<P><B>Abstract</B></P> <P>Cyclin-dependent kinase 5 (Cdk5) controls neuronal migration in the developing cortex when multipolar newborn neurons transform to become bipolar. However, by which mechanisms Cdk5 controls cell adhesion in migrating neurons are not fully understood. In this study, we examined the functional interaction between Cdk5 and N-cadherin (Ncad) in newborn neurons when they undergo the multipolar to bipolar transition in the intermediate zone (IZ). Detailed expression analysis revealed that both Cdk5 and Ncad were present in GFP-electroporated migrating neurons in the IZ. Misexpression of dominant negative Cdk5 into the embryonic brains stalled neuronal locomotion in the lower IZ in which arrested cells were round or multipolar. When Ncad was co-introduced with Cdk5DN, however, cells continue to migrate into the cortical plate (CP) and migrating neurons acquired typical bipolar morphology with a pia-directed leading process. Similarly, downregulation of CDK5 resulted in lesser aggregation ability, reversed by the expression of Ncad <I>in vitro</I>. Down-regulation of activity or protein level of CDK5 did not alter the total amount of NCAD proteins but lowered its surface expression in cells. Lastly, expression of CDK5 and NCAD overlapped in the IZ of the human fetal cortex, indicating that the role of Cdk5 and Ncad in neuronal migration is evolutionarily conserved.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Reduced Cdk5 activity inhibits the multipolar-bipolar transition of migrating neurons. </LI> <LI> Ncad expression rescues migration defects caused by the reduction of Cdk5 activity. </LI> <LI> Downregulation of Cdk5 impairs the membrane localization of Ncad. </LI> <LI> Cdk5 and Ncad are present in developing mouse and human brains. </LI> </UL> </P>
송호재,김근영,이아름,최용주,남경필,박준범,Song, Hojae,Kim, Geunyoung,Lee, Aleum,Choi, Yongju,Nam, Kyoungphile,Park, Junboum 한국지하수토양환경학회 2020 지하수토양환경 Vol.25 No.1
본 연구에서는 라돈가스의 환경적 문제점을 구체적으로 파악하였다. 각 나라별 라돈가스 환경문제 사례 분석을 통하여 국가별 라돈 가스 농도와 위험도를 조사하였다. 환경적 문제가 되는 라돈가스 유입의 방지법을 조사 및 연구하여 소개한다