http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Hassanain, Mazen (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Incorporation of water sludge, silica fume, and rice husk ash in brick making
Hegazy, Badr El-Din Ezzat,Fouad, Hanan Ahmed,Hassanain, Ahmed Mohammed Techno-Press 2012 Advances in environmental research Vol.1 No.1
The water sludge is generated from the treatment of water with alum. Disposing of sludge again to the streams raises the concentrations of aluminum oxides in water, which has been linked to Alzheimer's disease. The use of water treatment plant (WTP) sludge in manufacturing of constructional elements achieves both the economical and environmental benefits. Due to the similar mineralogical composition of clay and WTP sludge, this study investigated the complete substitution of brick clay by sludge incorporated with some of the agricultural and industrial wastes, such as rice husk ash (RHA) and silica fume (SF). Three different series of sludge to SF to RHA proportions by weight were tried, which were (25: 50: 25%), (50: 25: 25%), and (25: 25: 50%), respectively. Each brick series was fired at 900, 1000, 1100, and $1200^{\circ}C$. The physical and mechanical properties of the produced bricks were then determined and evaluated according to Egyptian Standard Specifications (E.S.S.) and compared to control clay-brick. From the obtained results, it was concluded that by operating at the temperature commonly practiced in the brick kiln, a mixture consists of 50% of sludge, 25% of SF, and 25% of RHA was the optimum materials proportions to produce brick from water sludge incorporated with SF and RHA. The produced bricks properties were obviously superior to the 100% clay control-brick and to those available in the Egyptian market.
-
Tumor Heterogeneity Predicts Metastatic Potential in Colorectal Cancer
Joung, Je-Gun,Oh, Bo Young,Hong, Hye Kyung,Al-Khalidi, Hisham,Al-Alem, Faisal,Lee, Hae-Ock,Bae, Joon Seol,Kim, Jinho,Cha, Hong-Ui,Alotaibi, Maram,Cho, Yong Beom,Hassanain, Mazen,Park, Woong-Yang,Lee, American Association for Cancer Research 2017 Clinical Cancer research Vol.23 No.23
<P><B>Purpose:</B> Tumors continuously evolve to maintain growth; secondary mutations facilitate this process, resulting in high tumor heterogeneity. In this study, we compared mutations in paired primary and metastatic colorectal cancer tumor samples to determine whether tumor heterogeneity can predict tumor metastasis.</P><P><B>Experimental Design:</B> Somatic variations in 46 pairs of matched primary-liver metastatic tumors and 42 primary tumors without metastasis were analyzed by whole-exome sequencing. Tumor clonality was estimated from single-nucleotide and copy-number variations. The correlation between clinical parameters of patients and clonal heterogeneity in liver metastasis was evaluated.</P><P><B>Results:</B> Tumor heterogeneity across colorectal cancer samples was highly variable; however, a high degree of tumor heterogeneity was associated with a worse disease-free survival. Highly heterogeneous primary colorectal cancer was correlated with a higher rate of liver metastasis. Recurrent somatic mutations in <I>APC, TP53</I>, and <I>KRAS</I> were frequently detected in highly heterogeneous colorectal cancer. The variant allele frequency of these mutations was high, while somatic mutations in other genes such as <I>PIK3CA</I> and <I>NOTCH1</I> were low. The number and distribution of primary colorectal cancer subclones were preserved in metastatic tumors.</P><P><B>Conclusions:</B> Heterogeneity of primary colorectal cancer tumors can predict the potential for liver metastasis and thus, clinical outcome of patients. <I>Clin Cancer Res; 23(23); 7209–16. ©2017 AACR</I>.</P>
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
