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        Chronic Rhinosinusitis and the Coagulation System

        김동영,Seong H. Cho,Tetsuji Takabayashi,Robert P. Schleimer 대한천식알레르기학회 2015 Allergy, Asthma & Immunology Research Vol.7 No.5

        Chronic rhinosinusitis (CRS) is one of the most common chronic diseases in adults and severely affects quality of life in patients. Although various etiologic and pathogenic mechanisms of CRS have been proposed, the causes of CRS remain uncertain. Abnormalities in the coagulation cascade may play an etiologic role in many diseases, such as asthma and other inflammatory conditions. While studies on the relationship between asthma and dysregulated coagulation have been reported, the role of the coagulation system in the pathogenesis of CRS has only been considered following recent reports. Excessive fibrin deposition is seen in nasal polyp (NP) tissue from patients with chronic rhinosinusitis with nasal polyp (CRSwNP) and is associated with activation of thrombin, reduction of tissue plasminogen activator (t-PA) and upregulation of coagulation factor XIII-A (FXIII-A), all events that can contribute to fibrin deposition and crosslinking. These findings were reproduced in a murine model of NP that was recently established. Elucidation of the mechanisms of fibrin deposition may enhance our understanding of tissue remodeling in the pathophysiology of NP and provide new targets for the treatment of CRSwNP.

      • Power Supply System of DC/AC Micro Grid System

        K.Yukita,K.Ban,Y.Goto,K.Ichiyanagi,K.Hirose,T.Ushirokawa,Y.Okui,H.Takabayashi 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5

        This paper proposes an AC/DC power supply system with DGs using the parallel processing method. The purpose of this system is to supply the power without connecting to the utility gird. The DGs consist of photovoltaic (PV), -and wind generators (WG), and the main energy source of this system is the DGs and the UPS battery. When the system does not get enough energy from the DGs, and the power supply of the battery runs out, this system connects to the utility grid and begins to charge the battery and supply to the load. In this study, we focused on the AC power supply and DC power supply from DGs. Then, the converters of DGs use two types, DC/AC type and DC/DC type. The power supply system has been operated with the actual loads of 20 ㎾ in the campus of the Aichi Institute of Technology. This paper reports on our study of DC and AC power supplies in the event of a system anomaly.

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