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      • KCI등재

        Delayed bipedicled nasolabial flap in facial reconstruction

        Cindy Siaw-Lin Goh,Joshua Guy Perrett,Manzhi Wong,Bien-Keem Tan 대한성형외과학회 2018 Archives of Plastic Surgery Vol.45 No.3

        Background The nasolabial flap is ideal for reconstruction of the nasal alar subunit due to its proximity, color and contour match, and well-placed donor scar. When raised as a random-pattern flap, there is a risk of vascular compromise to the tip with increased flap length and aggressive flap thinning. Surgical delay can greatly improve the chances of tip survival, allowing the harvest of longer flaps with greater reach. Methods We describe our technique of lengthening the nasolabial flap through multiple delay procedures. A bipedicled flap was first raised and then transferred as a unipedicled flap with a 6:1 length-to-width ratio. During the delay process, the flap tip was thinned to the subdermal layer. Results In our case series of seven patients, defects as far as the medial canthal area and contralateral ala were reconstructed successfully with no incidence of tip necrosis or flap loss. The resultant flaps were thin enough to be folded over for the reconstruction of alar rim defects. Conclusions We highlight the success of our surgical technique in creating thin and robust nasolabial flaps for the reconstruction of full-thickness defects around the nose.

      • Capturing Wetting States in Nanopatterned Silicon

        Xu, XiuMei,Vereecke, Guy,Chen, Chang,Pourtois, Geoffrey,Armini, Silvia,Verellen, Niels,Tsai, Wei-Kang,Kim, Dong-Wook,Lee, Eunsongyi,Lin, Chang-You,Van Dorpe, Pol,Struyf, Herbert,Holsteyns, Frank,Moshc American Chemical Society 2014 ACS NANO Vol.8 No.1

        <P>Spectacular progress in developing advanced Si circuits with reduced size, along the track of Moore’s law, has been relying on necessary developments in wet cleaning of nanopatterned Si wafers to provide contaminant free surfaces. The most efficient cleaning is achieved when complete wetting can be realized. In this work, ordered arrays of silicon nanopillars on a hitherto unexplored small scale have been used to study the wetting behavior on nanomodulated surfaces in a substantial range of surface treatments and geometrical parameters. With the use of optical reflectance measurements, the nanoscale water imbibition depths have been measured and the transition to the superhydrophobic Cassie–Baxter state has been accurately determined. For pillars of high aspect ratio (about 15), the transition occurs even when the surface is grafted with a hydrophilic functional group. We have found a striking consistent deviation between the contact angle measurements and the straightforward application of the classical wetting models. Molecular dynamics simulations show that these deviations can be attributed to the long overlooked atomic-scale surface perturbations that are introduced during the nanofabrication process. When the transition condition is approached, transient states of partial imbibition that characterize intermediate states between the Wenzel and Cassie–Baxter states are revealed in our experiments.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2014/ancac3.2014.8.issue-1/nn405621w/production/images/medium/nn-2013-05621w_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn405621w'>ACS Electronic Supporting Info</A></P>

      • SCOPUSKCI등재

        Delayed bipedicled nasolabial flap in facial reconstruction

        Goh, Cindy Siaw-Lin,Perrett, Joshua Guy,Wong, Manzhi,Tan, Bien-Keem Korean Society of Plastic and Reconstructive Surge 2018 Archives of Plastic Surgery Vol.45 No.3

        Background The nasolabial flap is ideal for reconstruction of the nasal alar subunit due to its proximity, color and contour match, and well-placed donor scar. When raised as a random-pattern flap, there is a risk of vascular compromise to the tip with increased flap length and aggressive flap thinning. Surgical delay can greatly improve the chances of tip survival, allowing the harvest of longer flaps with greater reach. Methods We describe our technique of lengthening the nasolabial flap through multiple delay procedures. A bipedicled flap was first raised and then transferred as a unipedicled flap with a 6:1 length-to-width ratio. During the delay process, the flap tip was thinned to the subdermal layer. Results In our case series of seven patients, defects as far as the medial canthal area and contralateral ala were reconstructed successfully with no incidence of tip necrosis or flap loss. The resultant flaps were thin enough to be folded over for the reconstruction of alar rim defects. Conclusions We highlight the success of our surgical technique in creating thin and robust nasolabial flaps for the reconstruction of full-thickness defects around the nose.

      • KCI등재후보

        Interactive Visualization for Patient-to-Patient Comparison

        Quang Vinh Nguyen,Guy Nelmes,Mao Lin Huang,Simeon Simoff,Daniel Catchpoole 한국유전체학회 2014 Genomics & informatics Vol.12 No.1

        A visual analysis approach and the developed supporting technology provide a comprehensive solution for analyzing largeand complex integrated genomic and biomedical data. This paper presents a methodology that is implemented as aninteractive visual analysis technology for extracting knowledge from complex genetic and clinical data and then visualizingit in a meaningful and interpretable way. By synergizing the domain knowledge into development and analysis processes, wehave developed a comprehensive tool that supports a seamless patient-to-patient analysis, from an overview of the patientpopulation in the similarity space to the detailed views of genes. The system consists of multiple components enabling thecomplete analysis process, including data mining, interactive visualization, analytical views, and gene comparison. Wedemonstrate our approach with medical scientists on a case study of childhood cancer patients on how they use the tool toconfirm existing hypotheses and to discover new scientific insights.

      • KCI등재

        Rupture of an Idiopathic Aneurysm of the Inferior Pancreaticoduodenal Artery Leading to an Intra-Abdominal Bleeding

        Riham Imam,Harbi Khalayleh,Deeb Khoury,Guy Lin,Ashraf Imam 대한외상중환자외과학회 2020 Journal of Acute Care Surgery Vol.10 No.1

        Aneurysm of the pancreaticoduodenal artery is a rare finding that can be divided into true and false aneurysm. True aneurysm of the pancreaticoduodenal artery is more common and is usually due to atherosclerosis or celiac stenosis. Herein we present a rare case of a 59-year-old male patient with a spontaneous rupture of an idiopathic aneurysm of the inferior pancreaticoduodenal artery who was successfully treated with angiographic coil embolization

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