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RISS 인기검색어
- 검색키워드
- 저자 : G. Uchida (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
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Generation of nitridated silicon nanoparticles and the application to solar cell
G. Uchida,Y. Kawashima,K. Yamamoto,M. Sato,K. Kamataki,N. Itagaki,K. Koga,M. Shiratani 한국표면공학회 2010 한국표면공학회 학술발표회 초록집 Vol.2010 No.11
Semiconductor nanocrystals have attracted much attention as materials for multiple-exciton generation (MEG) photovoltaics. Surface modification of such nanocrystals is important to make quantum well structure for efficient MEG as well as to extract photo-generated carriers from nanocrystals. In this study, nitridated silicon particles were produced by SiH₄/H₂/N₂ PECVD, where generation of silicon particles and their surface nitridation were independently controlled using two multi-hollow discharges. We observed strong photoluminescence (PL) emission in an energy range of 1.9 to 2.4 eV from Si particle, which may be explained by a quantum-confinement effect of silicon particles embedded in the thin film.
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Possible Translocation of Periodontal Pathogens into the Lymph Nodes Draining the Oral Cavity
G. Amodini Rajakaruna,Makoto Umeda,Keisuke Uchida,Asuka Furukawa,Bae Yuan,Yoshimi Suzuki,Ebe Noriko,Yuichi Izumi,Yoshinobu Eishi 한국미생물학회 2012 The journal of microbiology Vol.50 No.5
Numerous publications have reported the presence of periodontopathogenic bacteria in peripheral and central vascular lesions. However, it is unclear how this bacterial translocation occurs. The objective of this study was to investigate whether periodontopathic bacteria are translocated to lymph nodes proximal to the oral cavity. Obtaining lymph node samples is not ethically feasible unless they are excised as part of the surgical management of patients with cancer. This study analyzed formalin-fixed and paraffin-embedded lymph nodes, histologically negative for cancer cell invasion, that were excised from 66 patients with histories of head and neck cancer. Real-time PCR was performed to amplify the 16S ribosomal DNA fragments from Porphyromonas gingivalis,Treponema denticola, Aggregatibacter actinomycetemcomitans,Tannerella forsythia, and Prevotella intermedia. The relationship between bacterial detection and cancer severity,gender, and the use of anti-cancer therapy was examined by Fisher’s exact test. P. gingivalis, T. forsythia, and P. intermedia were present in 17%, 8%, and 8% of the samples of submandibular and submental lymph nodes, respectively. There were no significant relationships between bacterial detection and the cancer disease status, patient gender or use of anticancer therapy. According to these data, it appears that the translocation of periodontopathic bacteria may occur via lymphatic drainage, irrespective of the cancer disease status, gender or anticancer therapy.
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산소환원 및 산화니켈의 용해거동으로부터 본 삼원계 탄산염 전해질의 특성
Lee, C.G.,Taniguchi, T.,Uchida, I. 한국전기화학회 2003 한국전기화학회지 Vol.6 No.3
용융탄산염형 연료전지의 특성을 결정짓는 탄산염 전해질에 있어, 기존의 Li-K와 Li-Na 탄산염과는 다른 Li-Na-K 삼원계 탄산염의 특성을 산소환원 및 산화니켈 용해거동을 통해 검토하였다. 대상 삼원계 전해질은 Li-Na-K=47.4-32.6-20, 60-20-20, 50-40-10, $40-40-20mo1\%$이었으며, $650^{\circ}C$, 1기압 조건에서 산소환원 거동은 전기화학적 방법을 통해, NiO용해거동은 화학적 방법을 통해 검토하였다 삼원계 조성에 따라 산소환원 전류치의 차이가 관찰되어, 산소용해도가 조성에 의존함을 나타내었다. 또한 $Li-Na-K = 50-40-10 mol\%$ 조성에서는 다른 형태의 산소환원 피크가 관찰되어 조성에 따라 산소환원 메카니즘의 차이가 존재할 수 있음을 시사하였다. 그러나 산화니켈 용해도는 조성에 크게 의존하지 않는 특성을 보여주었다. The oxygen reduction and NiO dissolution behaviors in Li-Na-K three component carbonate melts have been investigated with various compositions through electrochemical and chemical ways. The oxygen reduction currents and NiO solubilities were measured at $650^{\circ}C$ and atmospheric condition in Li-Na-K =47.4-32.6-20, 60-20-20, 50-40-10, $40-40-20 mol\%$ carbonate melts. The oxygen reduction currents showed dependence on the composition, indicating oxygen solubility is a function of carbonate composition. At the composition of $ Li-Na-K=50-40-10 mol%$, a broader peak was observed, suggesting different oxygen reduction mechanism probably prevails in this composition. In contrast, insignificant differences of NiO solubility were obtained among the compositions.
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A critical step for JNK activation: isomerization by the prolyl isomerase Pin1
Park, J E,Lee, J A,Park, S G,Lee, D H,Kim, S J,Kim, H-J,Uchida, C,Uchida, T,Park, B C,Cho, S Macmillan Publishers Limited 2012 Cell death and differentiation Vol.19 No.1
c-Jun N-terminal kinase (JNK) is activated by dual phosphorylation of both threonine and tyrosine residues in the phosphorylation loop of the protein in response to several stress factors. However, the precise molecular mechanisms for activation after phosphorylation remain elusive. Here we show that Pin1, a peptidyl-prolyl isomerase, has a key role in the JNK1 activation process by modulating a phospho-Thr-Pro motif in the phosphorylation loop. Pin1 overexpression in human breast cancer cell lines correlates with increased JNK activity. In addition, small interfering RNA (siRNA) analyses showed that knockdown of Pin1 in a human breast cancer cell line decreased JNK1 activity. Pin1 associates with JNK1, and then catalyzes prolyl isomerization of the phospho-Thr-Pro motif in JNK1 from trans- to cis-conformation. Furthermore, Pin1 enhances the association of JNK1 with its substrates. As a result, Pin1<SUP>−/−</SUP> cells are defective in JNK activation and resistant to oxidative stress. These results provide novel insights that, following stress-induced phosphorylation of Thr in the Thr-Pro motif of JNK1, JNK1 associates with Pin1 and undergoes conformational changes to promote the binding of JNK1 to its substrates, resulting in cellular responses from extracellular signals.
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